Sheng Xinru, Li Errui, Zhou Yujuan, Zhao Run, Zhu Weijie, Huang Feihe
State Key Laboratory of Chemical Engineering, Center for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China.
J Am Chem Soc. 2020 Apr 1;142(13):6360-6364. doi: 10.1021/jacs.0c01274. Epub 2020 Mar 17.
Two monochloropyridine isomers, 2-chloropyridine () and 3-chloropyridine (), are in need of a more effective separation method besides rectification. Herein we offer a facile and energy-saving adsorptive separation strategy using nonporous adaptive crystals of perethylated pillar[5]arene (), perethylated pillar[6]arene (), perbromoethylated pillar[5]arene (), and perbromoethylated pillar[6]arene (), which possess different cavity sizes and substituents and have never been employed in the separation of single-substituted heterocyclic aromatic compounds. crystals show a marked preference for in the equimolar mixture of and , affording it with 96.4% purity. Single crystal diffraction experiments demonstrate that has stronger host-guest interactions with than . The cycling experiments demonstrate that crystals can be used at least five times without losing their adsorption selectivity or capacity.
除精馏外，两种一氯吡啶异构体，即2-氯吡啶（ ）和3-氯吡啶（ ），还需要一种更有效的分离方法。在此，我们提供了一种简便且节能的吸附分离策略，使用全乙基化的柱[5]芳烃（ ）、全乙基化的柱[6]芳烃（ ）、全溴乙基化的柱[5]芳烃（ ）和全溴乙基化的柱[6]芳烃（ ）的无孔自适应晶体，这些晶体具有不同的空腔尺寸和取代基，且从未用于单取代杂环芳烃化合物的分离。 晶体在 和 的等摩尔混合物中对 表现出明显的偏好，可使其纯度达到96.4%。单晶衍射实验表明， 与 的主客体相互作用比 更强。循环实验表明， 晶体至少可使用五次而不丧失其吸附选择性或容量。
