Dhadke Vithal Narayan, Dhadke Shubhangi V, Kulkarni Akshay
Professor and HOD.
Associate Professor, Department of Medicine, Dr. V.M. Govt. Medical College, Solapur, Maharashtra; Corresponding Author.
J Assoc Physicians India. 2020 Mar;68(3):33-35.
Cerebral venous sinus thrombosis (CVT) occurs due to occlusion of the veins and sinuses which drain the brain parenchyma. It is an uncommon form of stroke, predominantly found in young patients1 . Despite advances in the recognition of CVT in recent years, diagnosis and management can be difficult because of the diversity of underlying risk factors, presenting features and the absence of a uniform treatment approach. This study aimed to ascertain the clinical presentation, various aetiologies and prognostic indicators of cerebral venous sinus thrombosis.
This hospital-based descriptive study was carried out on 30 eligible patients from December 2013 to July 2015 after approval of Institutional Ethics Committee. Detailed history, clinical findings and required relevant investigations were recorded and analysed.
CVT was commonly observed in younger persons, commonly between 21-30 years. Female: Male ratio was 2.33. Altered sensorium at presentation was a poor prognostic indicator. The most common etiology was pregnancy and puerperium, followed by hyperhomocysteinemia. Superior sagittal sinus was found to be the most common site of thrombosis in this study, in 17 (56.7%) of the patients. 17 patients (56.67%) recovered completely without any neurodeficit. 24 ( 80%) and 22 (66%) subjects had cerebral infarction secondary to CVT. 5 (16.67%) patients succumbed to thrombosis or complications, most commonly due to intracerebral haemorrhage and cerebral edema.
CVT is a disease with multifactorial, gender-related specific causes and has a wide and varied clinical spectrum.
脑静脉窦血栓形成（CVT）是由于引流脑实质的静脉和静脉窦闭塞所致。它是一种不常见的中风形式，主要见于年轻患者。尽管近年来对CVT的认识有所进步，但由于潜在危险因素、临床表现的多样性以及缺乏统一的治疗方法，诊断和管理仍可能存在困难。本研究旨在确定脑静脉窦血栓形成的临床表现、各种病因及预后指标。
本研究为基于医院的描述性研究，于2013年12月至2015年7月在机构伦理委员会批准后，对30例符合条件的患者进行。记录并分析详细病史、临床发现及所需的相关检查。
CVT常见于年轻人，通常在21 - 30岁之间。女性与男性比例为2.33。就诊时意识改变是不良预后指标。最常见的病因是妊娠和产褥期，其次是高同型半胱氨酸血症。在本研究中，上矢状窦是最常见的血栓形成部位，17例（56.7%）患者受累。17例患者（56.67%）完全康复，无任何神经功能缺损。24例（80%）和22例（66%）患者继发于CVT的脑梗死。5例（16.67%）患者死于血栓形成或并发症，最常见的原因是脑出血和脑水肿。
CVT是一种具有多因素、性别相关特定病因且临床谱广泛多样的疾病。
