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Comparing clinical trial population representativeness to real-world populations: an external validity analysis encompassing 43 895 trials and 5 685 738 individuals across 989 unique drugs and 286 conditions in England.比较临床试验人群代表性与真实世界人群:一项涵盖英国989种独特药物和286种病症的43895项试验及5685738名个体的外部有效性分析。
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What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review.成年人使用移动应用程序进行糖尿病自我管理的认知和体验如何?一项系统综述。
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Patient perspectives on the use of mobile apps to support heart failure management: A qualitative descriptive study.患者对使用移动应用程序支持心力衰竭管理的看法:定性描述性研究。
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Association of multimorbidity patterns with incident disability and recovery of independence among middle-aged and older adults.多种共存疾病模式与中年和老年人残疾发生和独立恢复的关系。
Age Ageing. 2022 Aug 2;51(8). doi: 10.1093/ageing/afac177.
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Different definitions of multimorbidity and their effect on prevalence rates: a retrospective study in German general practices.多种疾病的不同定义及其对患病率的影响:德国普通实践中的回顾性研究。
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A flexible protocol for a systematic review of remote patient monitoring.一种远程患者监测系统评价的灵活方案。
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本文引用的文献

1
Managing multimorbidity: Profiles of integrated care approaches targeting people with multiple chronic conditions in Europe.管理多重疾病:针对欧洲多种慢性疾病患者的综合护理方法简介。
Health Policy. 2018 Jan;122(1):44-52. doi: 10.1016/j.healthpol.2017.10.002. Epub 2017 Oct 19.
2
Cochrane Review Summary: Interventions for improving outcomes in patients with multimorbidity in primary care and community settings.Cochrane系统评价总结:改善基层医疗和社区环境中多病共存患者结局的干预措施。
Prim Health Care Res Dev. 2017 Mar;18(2):109-111. doi: 10.1017/S1463423616000426. Epub 2016 Dec 20.
3
Association Between Lifestyle Factors and the Incidence of Multimorbidity in an Older English Population.英国老年人群生活方式因素与多种疾病共病发生率之间的关联
J Gerontol A Biol Sci Med Sci. 2017 Apr 1;72(4):528-534. doi: 10.1093/gerona/glw146.
4
Clinical workload in UK primary care: a retrospective analysis of 100 million consultations in England, 2007-14.英国初级医疗保健的临床工作量:对2007 - 2014年英格兰1亿次诊疗的回顾性分析。
Lancet. 2016 Jun 4;387(10035):2323-2330. doi: 10.1016/S0140-6736(16)00620-6. Epub 2016 Apr 5.
5
Long terms trends of multimorbidity and association with physical activity in older English population.英国老年人群中多种疾病的长期趋势及其与身体活动的关联
Int J Behav Nutr Phys Act. 2016 Jan 19;13:8. doi: 10.1186/s12966-016-0330-9.
6
Multiple chronic conditions and life expectancy: a life table analysis.多种慢性病与预期寿命:一项生命表分析
Med Care. 2014 Aug;52(8):688-94. doi: 10.1097/MLR.0000000000000166.
7
The content of general practice consultations: cross-sectional study based on video recordings.全科诊疗内容:基于视频记录的横断面研究。
Br J Gen Pract. 2013 Nov;63(616):e751-9. doi: 10.3399/bjgp13X674431.
8
Quality of care for patients with multiple chronic conditions: the role of comorbidity interrelatedness.患有多种慢性病患者的护理质量:共病相关性的作用。
J Gen Intern Med. 2014 Mar;29(3):529-37. doi: 10.1007/s11606-013-2616-9. Epub 2013 Oct 1.
9
Relative impact of multimorbid chronic conditions on health-related quality of life--results from the MultiCare Cohort Study.多慢性合并症对健康相关生活质量的相对影响——来自 MultiCare 队列研究的结果。
PLoS One. 2013 Jun 24;8(6):e66742. doi: 10.1371/journal.pone.0066742. Print 2013.
10
Multimorbidity, polypharmacy, referrals, and adverse drug events: are we doing things well?多发病共存、多种药物并用、转诊和药物不良事件:我们做得好吗?
Br J Gen Pract. 2012 Dec;62(605):e821-6. doi: 10.3399/bjgp12X659295.

The multimorbidity epidemic: challenges for real-world research.

作者信息

Adan Muna, Gillies Clare, Tyrer Freya, Khunti Kamlesh

机构信息

Pharmacoepidemiologist, Department of Health Sciences, University of Leicester, Leicester, UK.

Lecturer in Medical Statistics, Department of Health Sciences, University of Leicester, Leicester, UK.

出版信息

Prim Health Care Res Dev. 2020 Mar 6;21:e6. doi: 10.1017/S146342361900094X.

DOI:10.1017/S146342361900094X
PMID:32138803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7082712/
Abstract
摘要