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加速康复外科路径中各环节遵医行为对胸腔镜解剖性肺切除术结局的影响。

Impact of Compliance With Components of an ERAS Pathway on the Outcomes of Anatomic VATS Pulmonary Resections.

机构信息

Service of Thoracic Surgery, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

Service of Thoracic Surgery, Lausanne University Hospital (CHUV), Lausanne, Switzerland; Faculty of Biology and Medicine, University of Lausanne (UNIL), Lausanne, Switzerland.

出版信息

J Cardiothorac Vasc Anesth. 2020 Jul;34(7):1858-1866. doi: 10.1053/j.jvca.2020.01.038. Epub 2020 Jan 25.

Abstract

OBJECTIVES

Implementation of an Enhanced Recovery After Surgery (ERAS) program is associated with better postoperative outcomes. The aim of this study was to evaluate the impact of ERAS compliance (overall and to specific elements of the program) on them.

DESIGN

Retrospective analysis of prospectively collected data.

SETTING

University hospital, monocentric.

PARTICIPANTS

All adult (≥18 years old) patients undergoing video-assisted thoracic surgery (VATS) anatomic pulmonary resection.

INTERVENTIONS

ERAS-governed VATS anatomic pulmonary resection.

MEASUREMENTS AND MAIN RESULTS

Demographics, surgical characteristics and pre-, peri-, and postoperative compliance with 16 elements of the ERAS program were assessed. Postoperative outcomes and length of stay were compared between low- (<75% of adherence) and high-compliance (≥75%) groups. From April 2017 to November 2018, 192 ERAS patients (female/male: 98/94) of median age of 66 years (interquartile range 58-71) underwent VATS resection (109 lobectomies, 83 segmentectomies). There was no 30-day mortality and resurgery rate was 5.7%. Overall ERAS compliance was 76%. High compliance was associated with fewer complications (18% v 48%, p < 0.0001) and lower rate of delayed discharge (37% v 60%, p = 0.0013). Early removal of chest tubes (odds ratio [OR]: 0.26, p < 0.002), use of electronic drainage (OR: 0.39, p = 0.036), opioid cessation on day 3 (OR: 0.28, p = 0.016), and early feeding (OR: 0.12, p = 0.014) were associated with reduced rates of postoperative complications. Shorter hospital stay was correlated with early removal of chest tubes (OR: 0.12, p < 0.0001) and opioid cessation on day 3 (OR: 0.23, p = 0.001).

CONCLUSIONS

High ERAS compliance is associated with better postoperative outcomes in patients undergoing anatomic pulmonary VATS resections.

摘要

目的

实施加速康复外科(ERAS)方案与更好的术后结果相关。本研究旨在评估 ERAS 依从性(总体和方案的具体要素)对这些结果的影响。

设计

前瞻性收集数据的回顾性分析。

设置

大学医院,单中心。

参与者

所有接受电视辅助胸腔镜手术(VATS)解剖性肺切除术的成年(≥18 岁)患者。

干预措施

ERAS 指导的 VATS 解剖性肺切除术。

测量和主要结果

评估人口统计学、手术特征以及术前、术中和术后对 ERAS 方案 16 个要素的依从性。比较低依从性(<75%)和高依从性(≥75%)组之间的术后结果和住院时间。2017 年 4 月至 2018 年 11 月,192 例接受 ERAS 治疗的患者(女性/男性:98/94)行 VATS 切除术(109 例肺叶切除术,83 例肺段切除术),中位年龄为 66 岁(四分位距 58-71)。无 30 天死亡率,再次手术率为 5.7%。总体 ERAS 依从性为 76%。高依从性与较少的并发症(18%比 48%,p<0.0001)和较低的延迟出院率(37%比 60%,p=0.0013)相关。尽早拔除胸腔引流管(优势比 [OR]:0.26,p<0.002)、使用电子引流(OR:0.39,p=0.036)、术后第 3 天停止使用阿片类药物(OR:0.28,p=0.016)和早期进食(OR:0.12,p=0.014)与降低术后并发症发生率相关。较短的住院时间与尽早拔除胸腔引流管(OR:0.12,p<0.0001)和术后第 3 天停止使用阿片类药物(OR:0.23,p=0.001)相关。

结论

在接受解剖性 VATS 肺切除术的患者中,较高的 ERAS 依从性与更好的术后结果相关。

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