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局部应用氨甲环酸与局部应用羟甲唑啉喷雾剂治疗鼻出血时的止血数据。

Data on the hemostasis in epistaxis with Topically Administered TXA Versus Topical Oxymetazoline Spray.

作者信息

Whitworth Kristen, Johnson Jacob, Wisniewski Samuel, Schrader Meghan

机构信息

Lakeland Health, United States.

Michigan State University College of Osteopathic Medicine, United States.

出版信息

Data Brief. 2020 Feb 13;29:105283. doi: 10.1016/j.dib.2020.105283. eCollection 2020 Apr.

DOI:10.1016/j.dib.2020.105283
PMID:32140505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7047014/
Abstract

The use of tranexamic acid (TXA) has recently gained popularity as a treatment modality for epistaxis in the emergency department. Data are presented on the efficacy of the topical use of the intravenous formulation of TXA versus the vasoconstrictor oxymetazoline applied topically in achieving hemostasis in patient presenting to the emergency department with anterior epistaxis. The original article "Comparative Effectiveness of Topically Administered TXA Versus Topical Oxymetazoline Spray for Achieving Hemostasis in Epistaxis" [1] provides complete interpretation of the data. The dataset regarding these treatment modalities has clinical significance toward preventing an avoidable need for escalation of treatment that could potentially increase patient discomfort and prolong emergency department throughput time.

摘要

氨甲环酸(TXA)作为急诊科鼻出血的一种治疗方式,近来受到广泛应用。本文呈现了静脉用TXA局部应用与局部应用血管收缩剂羟甲唑啉在急诊科前位鼻出血患者止血效果的数据对比。原文《局部应用TXA与局部应用羟甲唑啉喷雾剂治疗鼻出血的止血效果比较》[1]对这些数据进行了完整解读。关于这些治疗方式的数据集对于避免不必要的治疗升级具有临床意义,这种升级可能会增加患者不适并延长急诊科的就诊时间。

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Data on the hemostasis in epistaxis with Topically Administered TXA Versus Topical Oxymetazoline Spray.局部应用氨甲环酸与局部应用羟甲唑啉喷雾剂治疗鼻出血时的止血数据。
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Comparative Effectiveness of Topically Administered Tranexamic Acid Versus Topical Oxymetazoline Spray for Achieving Hemostasis in Epistaxis.局部应用氨甲环酸与局部应用羟甲唑啉喷雾剂治疗鼻出血的止血效果比较。
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Adv Biomed Res. 2023 Jul 27;12:193. doi: 10.4103/abr.abr_247_22. eCollection 2023.
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Epistaxis Treatment Options: Literature Review.鼻出血的治疗选择:文献综述
Indian J Otolaryngol Head Neck Surg. 2023 Sep;75(3):2235-2244. doi: 10.1007/s12070-023-03824-z. Epub 2023 May 8.

本文引用的文献

1
Comparative Effectiveness of Topically Administered Tranexamic Acid Versus Topical Oxymetazoline Spray for Achieving Hemostasis in Epistaxis.局部应用氨甲环酸与局部应用羟甲唑啉喷雾剂治疗鼻出血的止血效果比较。
J Emerg Med. 2020 Feb;58(2):211-216. doi: 10.1016/j.jemermed.2019.11.038. Epub 2019 Dec 30.