Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe, Japan.
Department of Radiology, Hyogo Brain and Heart Center at Himeji, Himeji, Japan.
Cardiovasc Intervent Radiol. 2020 May;43(5):696-705. doi: 10.1007/s00270-020-02436-2. Epub 2020 Mar 5.
To evaluate the mid-term outcomes of transarterial embolization (TAE) for type II endoleak after endovascular abdominal aortic aneurysm repair (EVAR) and investigate the predictors of sac enlargement after embolization.
We conducted a retrospective analysis of 55 patients [48 men and 7 women, median age 79.0 (interquartile ranges 74-82) years] who underwent TAE for type II endoleak from 2010 to 2018. The aneurysmal sac enlargement, endoleaks, aneurysm-related adverse event rate, and reintervention rate were evaluated. Patients' characteristics and clinical factors were evaluated for their association with sac enlargement.
Fifty-five patients underwent TAE with technical success and were subsequently followed for a median of 636 (interquartile ranges 446-1292) days. The freedom from sac enlargement rates at 1, 3, and 5 years was 73.2%, 32.0%, and 26.7%, respectively. After initial TAE, the recurrent type II, delayed type I, and occult type III endoleak were identified in 39 (71%), 5 (9%), and 3 (5%) patients, respectively. Although a patient had aorto-duodenal fistula, there was no aneurysm-related death. The freedom from reintervention rates was 84.6%, 35.7%, and 17.0%, respectively. In the multivariate analysis, sac diameter > 55 mm at initial TAE (hazard ratios, 3.23; 95% confidence intervals, 1.22-8.58; P < 0.05) was a significant predictor of sac enlargement.
TAE for type II endoleak was not effective in preventing sac enlargement, and reinterventions were required among the mid-term follow-up. The sac diameter > 55 mm at initial TAE was a significant predictor of sac enlargement.
评估血管内腹主动脉瘤修复(EVAR)后经动脉栓塞(TAE)治疗 II 型内漏的中期结果,并探讨栓塞后瘤囊增大的预测因素。
我们对 2010 年至 2018 年期间接受 TAE 治疗的 55 例(48 名男性,7 名女性,中位年龄 79.0(四分位间距 74-82)岁)患者进行了回顾性分析。评估了瘤囊增大、内漏、与动脉瘤相关的不良事件发生率和再介入率。评估了患者的特征和临床因素与瘤囊增大的关系。
55 例患者行 TAE 治疗,技术成功率高,随后中位随访 636(四分位间距 446-1292)天。1、3、5 年无瘤囊增大率分别为 73.2%、32.0%和 26.7%。初次 TAE 后,39 例(71%)患者分别发现复发性 II 型、迟发性 I 型和隐匿性 III 型内漏,5 例(9%)和 3 例(5%)患者分别发现。尽管有 1 例患者发生了主动脉-十二指肠瘘,但无动脉瘤相关死亡。再介入率分别为 84.6%、35.7%和 17.0%。多变量分析显示,初次 TAE 时瘤囊直径>55mm(风险比,3.23;95%置信区间,1.22-8.58;P<0.05)是瘤囊增大的显著预测因素。
TAE 治疗 II 型内漏不能有效预防瘤囊增大,在中期随访中需要再次介入治疗。初次 TAE 时瘤囊直径>55mm 是瘤囊增大的显著预测因素。