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孕妇自主神经功能紊乱综合征。

Autonomic dysfunction syndrome in pregnant women.

机构信息

Department of Neurology, Novosibirsk State Medical University, 6 Zalesskii Str., Building 4, 630047, Novosibirsk, Russian Federation.

National Children's Rehabilitation Center, 36 Turan Str., 010000, Nur-Sultan, Republic of Kazakhstan.

出版信息

Acta Neurol Belg. 2021 Dec;121(6):1429-1433. doi: 10.1007/s13760-020-01312-7. Epub 2020 Mar 5.

Abstract

Available studies and information on the regulatory effect of the autonomic nervous system (ANS) in pregnancy are insufficient and contradictory due to a variety of research methods of ANS, the lack of a single standardized approach to the assessment of the functional tone of the ANS departments, and interpretation of the results. The aim of the study is investigation and predictive assessment of clinical and laboratory data in pregnant women with suprasegmental autonomic dysfunction with or without hypertension to determine the main directions of effective prevention of the nervous system damage. The material of the study included 206 pregnant women diagnosed with the syndrome of autonomic dysfunction in different variants. Age ranged from 17 to 47 years. All pregnant women had the following laboratory tests: general clinical tests, biochemical blood tests, including prothrombin index, fibrinogen, von Willebrand factor activity. The clinical and laboratory data were analyzed in pregnant women with autonomic dysfunction with or without hypertension. According to the results, it was found that in all groups of pregnant women a sympathetic effect prevails. This study showed that in the group of normotensive pregnant women, the main symptom is venous dysfunction, which poses a risk of an adverse course of cerebrovascular disease.

摘要

由于自主神经系统 (ANS) 的各种研究方法、缺乏单一的标准化方法来评估 ANS 部门的功能紧张度以及结果的解释,因此关于自主神经系统在妊娠中的调节作用的现有研究和信息是不足和矛盾的。本研究的目的是调查和预测有或没有高血压的超节段自主神经功能障碍孕妇的临床和实验室数据,以确定有效预防神经系统损伤的主要方向。研究材料包括 206 名被诊断为自主神经功能障碍综合征的不同变异的孕妇。年龄在 17 至 47 岁之间。所有孕妇均进行了以下实验室检查:一般临床检查、生化血液检查,包括凝血酶原指数、纤维蛋白原、血管性血友病因子活性。分析了有或没有高血压的自主神经功能障碍孕妇的临床和实验室数据。结果发现,在所有孕妇组中,交感神经作用占主导地位。这项研究表明,在正常血压孕妇组中,主要症状是静脉功能障碍,这增加了脑血管疾病不良病程的风险。

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