坎格雷洛和肝素在肝素诱导的血小板减少症患者肺血栓内膜切除术的应用。
Cangrelor and Heparin for Pulmonary Thromboendarterectomy in Heparin-Induced Thrombocytopenia.
机构信息
Department of Anesthesiology, Temple University Hospital, Philadelphia, Pennsylvania.
Department of Cardiology, Temple University Hospital, Philadelphia, Pennsylvania.
出版信息
Ann Thorac Surg. 2020 Sep;110(3):e161-e163. doi: 10.1016/j.athoracsur.2020.01.051. Epub 2020 Mar 3.
Perioperative anticoagulation management for patients with heparin-induced thrombocytopenia requiring cardiopulmonary bypass and deep hypothermic circulatory arrest presents a clinical challenge. Alternative anticoagulants have been used but can cause significant postoperative bleeding. We report the successful use of cangrelor and heparin in a 30-year-old patient with severe heparin-induced thrombocytopenia undergoing urgent pulmonary thromboendarterectomy.
对于需要体外循环和深低温停循环的肝素诱导血小板减少症患者，围手术期抗凝管理是一项临床挑战。已经使用了替代抗凝剂，但会导致明显的术后出血。我们报告了一例 30 岁严重肝素诱导血小板减少症患者成功使用坎格雷洛和肝素进行紧急肺动脉血栓内膜切除术的情况。
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