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腹腔镜治疗有或无网片加强的巨大食管裂孔疝:系统评价和荟萃分析。

Laparoscopic treatment of giant hiatal hernia with or without mesh reinforcement: A systematic review and meta-analysis.

机构信息

Faculdade de Medicina de Jundiaí, FMJ, Jundiaí, SP, Brazil.

Faculdade de Medicina de Jundiaí, FMJ, Jundiaí, SP, Brazil.

出版信息

Int J Surg. 2020 May;77:97-104. doi: 10.1016/j.ijsu.2020.02.036. Epub 2020 Mar 3.

DOI:10.1016/j.ijsu.2020.02.036
PMID:32142902
Abstract

BACKGROUND

The use of mesh associated with cruroplasty is still controversial, especially in cases of giant hernias, due to possible complications of the prosthesis reported in the literature, such as infection, chest migration, shrinkage, esophageal and aortic erosion, stenosis and obstruction. This systematic review and meta-analysis aimed to compare the use or not of mesh as a reinforcement in the laparoscopic repair of giant hernias and to determine which technique has the best results in recurrence and complication rates.

MATERIAL AND METHODS

A search was conducted using databases and included prospective and randomized studies. The studies should include patients with giant hernias who have undergone laparoscopic treatment comparatively analyzed between cruroplasty and suture associated with prosthetic reinforcement.

RESULTS

Of the 768 articles analyzed, 8 were selected for systematic review, and 7 were included in the meta-analysis (3 randomized trials with higher evidence strength, 2 randomized trials with lower methodological quality, and 2 prospective cohorts). The meta-analysis showed no statistically significant differences in favor of any of the intervention methods (mesh versus suture cruroplasty) for the different outcomes evaluated: recurrence (RD -0.06, CI [-0.13,0.01], I 22%, p 0.27); postoperative complications (RD 0.04, CI [-0.01,0.9], I 5%, p 0.30); deaths (RD -0.01, CI [-0.04, 0.02], I 0%, p 74); intraoperative complications (RD -0.03, CI [-0.07, 0.1]); reoperation (RD -0.04, CI [-0.10, 0.02], p 0.14).

CONCLUSION

There is no evidence supporting that routine mesh reinforcement in laparoscopic repair of giant hernias decreases recurrence and other complications. Systematic review registration number at PROSPERO: CRD42019147468.

摘要

背景

在巨大疝的情况下,由于文献中报道的假体相关并发症,如感染、胸部迁移、收缩、食管和主动脉侵蚀、狭窄和梗阻,使用网片与耻骨成型术相关联仍然存在争议。本系统评价和荟萃分析旨在比较在腹腔镜修复巨大疝时使用或不使用网片作为加强的效果,并确定哪种技术在复发和并发症发生率方面具有最佳结果。

材料和方法

使用数据库进行了搜索,并纳入了前瞻性和随机研究。这些研究应包括接受过腹腔镜治疗的巨大疝患者,对耻骨成型术和假体加强的缝合进行比较分析。

结果

在分析的 768 篇文章中,有 8 篇被选为系统评价,7 篇被纳入荟萃分析(3 项具有较高证据强度的随机试验、2 项方法学质量较低的随机试验和 2 项前瞻性队列研究)。荟萃分析显示,对于不同的评估结果,任何干预方法(网片与缝合耻骨成型术)之间均无统计学意义上的差异:复发(RD-0.06,CI[-0.13,0.01],I²2%,p0.27);术后并发症(RD0.04,CI[-0.01,0.9],I5%,p0.30);死亡(RD-0.01,CI[-0.04,0.02],I0%,p74);术中并发症(RD-0.03,CI[-0.07,0.1]);再次手术(RD-0.04,CI[-0.10,0.02],p0.14)。

结论

没有证据表明在腹腔镜修复巨大疝时常规网片加强可降低复发和其他并发症的发生率。系统评价在 PROSPERO 注册号:CRD42019147468。

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