Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea.
Department of Dermatology, College of Medicine, Dankook University, Cheonan, Korea.
Photochem Photobiol. 2020 Jul;96(4):738-740. doi: 10.1111/php.13260. Epub 2020 May 29.
The recent guideline on the management of urticaria recommends second-generation H1 antihistamine as the first-line therapy, with dose increases of up to fourfold and the addition of omalizumab or cyclosporine if inadequately controlled. However, the treatment of chronic spontaneous urticaria (CSU) is often disappointing. Therefore, a safe and effective treatment option is needed for refractory CSU. To evaluate whether phototherapy can relieve urticarial symptoms and serve as an additional treatment for CSU uncontrolled with antihistamine, we performed a qualitative systematic review. Our result suggests that NBUVB could be an effective complementary treatment modality to manage refractory CSU.
最近关于荨麻疹管理的指南建议第二代 H1 抗组胺药作为一线治疗药物，如果控制不佳，则增加剂量四倍，并添加奥马珠单抗或环孢素。然而，慢性自发性荨麻疹 (CSU) 的治疗往往令人失望。因此，需要为难治性 CSU 提供安全有效的治疗选择。为了评估光疗是否可以缓解荨麻疹症状并作为抗组胺药治疗控制不佳的 CSU 的附加治疗，我们进行了定性系统评价。我们的结果表明，NBUVB 可能是一种有效的补充治疗方式，可用于管理难治性 CSU。
