血清素与P物质：呼吸控制中的协同作用还是竞争关系。
Serotonin and substance P: Synergy or competition in the control of breathing.
作者信息
Szereda-Przestaszewska Małgorzata, Kaczyńska Katarzyna
机构信息
Department of Respiration Physiology, Mossakowski Medical Research Centre Polish Academy of Sciences, A. Pawińskiego 5, 02-106 Warsaw, Poland.
Department of Respiration Physiology, Mossakowski Medical Research Centre Polish Academy of Sciences, A. Pawińskiego 5, 02-106 Warsaw, Poland.
出版信息
Auton Neurosci. 2020 May;225:102658. doi: 10.1016/j.autneu.2020.102658. Epub 2020 Feb 26.
Numerous neurotransmitters identified in the central nervous system play role in ventilatory control. This mini-review focuses on the respiratory effects of two neurotransmitters: serotonin (5-HT) and substance P (SP). We discuss their co-localization in medullary raphe nuclei, expression of proper receptors within the specific regions of respiratory related structures and contribution to respiratory rhythmogenesis.
在中枢神经系统中发现的众多神经递质在通气控制中发挥作用。本综述聚焦于两种神经递质的呼吸效应：5-羟色胺（5-HT）和P物质（SP）。我们讨论它们在延髓中缝核的共定位、在呼吸相关结构特定区域内相应受体的表达以及对呼吸节律产生的作用。
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