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用于诊断人工关节感染的氟代脱氧葡萄糖正电子发射断层显像(F-FDG PET)

F-FDG PET for Diagnosing Infections in Prosthetic Joints.

作者信息

Kwee Robert M, Kwee Thomas C

机构信息

Department of Radiology, Zuyderland Medical Center, Heerlen/Sittard/Geleen, The Netherlands.

Department of Radiology, Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30.001, Groningen 9700 RB, the Netherlands.

出版信息

PET Clin. 2020 Apr;15(2):197-205. doi: 10.1016/j.cpet.2019.11.005.


DOI:10.1016/j.cpet.2019.11.005
PMID:32145890
Abstract

Periprosthetic joint infection (PJI) is a severe complication, associated with substantial morbidity and high costs. PJI can occur in the early postoperative period but also many years after joint replacement. Timely and accurate diagnosis is important for treatment planning. Diagnosis of PJI can be a challenge, especially for chronic and low-grade infections. The diagnostic performance of fludeoxyglucose F 18 (F-FDG) positron emission tomography (PET) in detecting PJI seems sufficiently high for routine clinical application and has additional value to conventional tests. Further research is needed to determine the exact place of F-FDG PET in the diagnostic work-up of suspected PJI.

摘要

人工关节周围感染(PJI)是一种严重的并发症,会导致较高的发病率和高昂的费用。PJI可发生在术后早期,也可在关节置换多年后出现。及时准确的诊断对于治疗方案的制定至关重要。PJI的诊断可能具有挑战性,尤其是对于慢性和低度感染。氟脱氧葡萄糖F 18(F-FDG)正电子发射断层扫描(PET)在检测PJI方面的诊断性能似乎足以用于常规临床应用,并且对传统检测具有附加价值。需要进一步研究以确定F-FDG PET在疑似PJI诊断检查中的确切地位。

相似文献

[1]
F-FDG PET for Diagnosing Infections in Prosthetic Joints.

PET Clin. 2020-4

[2]
Diagnostic utility of fluorodeoxyglucose positron emission tomography in prosthetic joint infection based on MSIS criteria.

Bone Joint J. 2019-8

[3]
Fluorodeoxyglucose positron emission tomography imaging for diagnosing periprosthetic hip infection: the importance of diagnostic criteria.

Int Orthop. 2018-9

[4]
18F FDG-PET/CT has poor diagnostic accuracy in diagnosing shoulder PJI.

Eur J Nucl Med Mol Imaging. 2019-7-11

[5]
Added value of 18F-FDG PET/CT in diagnosing infected hip prosthesis.

Acta Radiol. 2018-5

[6]
Improving the Diagnostic Performance of F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography in Prosthetic Heart Valve Endocarditis.

Circulation. 2018-10-2

[7]
Potential clinical implication of (18) F-FDG PET/CT in diagnosis of periprosthetic infection and its comparison with (18) F-Fluoride PET/CT.

J Med Imaging Radiat Oncol. 2016-6

[8]
The implications of 18F-FDG PET for the diagnosis of endoprosthetic loosening and infection in hip and knee arthroplasty: results from a prospective, blinded study.

BMC Musculoskelet Disord. 2006-3-3

[9]
The importance of the location of fluorodeoxyglucose uptake in periprosthetic infection in painful hip prostheses.

Nucl Med Commun. 2002-9

[10]
Usefulness of F-FDG PET/CT in a case of suspected vascular graft infection.

Rev Esp Med Nucl Imagen Mol. 2017

引用本文的文献

[1]
D-Glucose and its derivatives labeled with radioactive carbon and hydrogen: key tools for investigating biological processes and molecular mechanisms.

EJNMMI Radiopharm Chem. 2025-5-30

[2]
The Accuracy of Empirical Antibiotic Treatment for Periprosthetic Joint Infections in Total Shoulder and Knee Arthroplasties.

Antibiotics (Basel). 2025-4-28

[3]
Imaging in Periprosthetic Joint Infection Diagnosis: A Comprehensive Review.

Microorganisms. 2024-12-24

[4]
The Challenge of Periprosthetic Joint Infection Diagnosis: From Current Methods to Emerging Biomarkers.

Int J Mol Sci. 2023-2-21

[5]
SPECT/CT, PET/CT and PET/MRI: oncologic and infectious applications and protocol considerations.

Pediatr Radiol. 2023-6

[6]
Application of Ga-citrate PET/CT for differentiating periprosthetic joint infection from aseptic loosening after joint replacement surgery.

Bone Joint Res. 2022-6

[7]
A Systematic Review and Meta-Analysis on the Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for Diagnosing Periprosthetic Joint Infections.

Front Surg. 2022-6-1

[8]
Simultaneous F-FDG-PET/MRI for the detection of periprosthetic joint infections after knee or hip arthroplasty: a prospective feasibility study.

Int Orthop. 2022-9

[9]
The Role of Nuclear Medicine Imaging with F-FDG PET/CT, Combined In-WBC/Tc-Nanocoll, and Tc-HDP SPECT/CT in the Evaluation of Patients with Chronic Problems after TKA or THA in a Prospective Study.

Diagnostics (Basel). 2022-3-10

[10]
Use of PET-CT in diagnostic workup of periprosthetic infection of hip and knee joints: significance in detecting additional infectious focus.

Int Orthop. 2022-3

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