Suppr超能文献

脊柱转移瘤的杂交治疗。

Hybrid Therapy for Spinal Metastases.

机构信息

Department of Neurosurgery, Mount Sinai Hospital, New York, NY, USA.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

Neurosurg Clin N Am. 2020 Apr;31(2):191-200. doi: 10.1016/j.nec.2019.11.001. Epub 2020 Jan 24.

Abstract

The combination of separation surgery and stereotactic body radiotherapy optimizes the treatment of metastatic spine tumors. The integration of SBRT into treatment paradigms produces superb local control rates and consequently has diminished the role of surgery from principle treatment to one of adjuvant therapy. Under this paradigm, hybrid therapy for the treatment of metastatic spine tumors employs separation surgery to decompress the spinal cord and stabilize the spine while creating a safe target for ablative SBRT. Hybrid therapy is well tolerated, allows an early return to systemic therapy, and provides durable, local tumor control compared with more aggressive traditional approaches.

摘要

分离手术和立体定向体放射治疗的结合优化了转移性脊柱肿瘤的治疗。SBRT 融入治疗模式产生了极好的局部控制率,从而使手术从主要治疗方法转变为辅助治疗方法。在这种模式下,治疗转移性脊柱肿瘤的混合疗法采用分离手术来解除脊髓压迫并稳定脊柱,同时为消融性 SBRT 创建一个安全的靶区。与更激进的传统方法相比,混合疗法具有良好的耐受性,可早期恢复全身治疗,并提供持久的局部肿瘤控制。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验