Bhavana Appikatla Madhu, Kumari Pilli Hema Prakash, Mohan Nitin, Chandrasekhar Vijayalakshmai, Vijayalakshmi Payala, Manasa Rongala Venkata
Department of Microbiology, GITAM Institute of Medical Sciences and Research, Visakhapatnam, Andhra Pradesh, India.
Department of Obstetrics and Gynaecology, GITAM Institute of Medical Sciences and Research, Visakhapatnam, Andhra Pradesh, India.
Iran J Microbiol. 2019 Dec;11(6):488-495.
The association between bacterial vaginosis and urinary tract infection (UTI) in pregnant women is at a greater risk comparatively than patients with bacterial vaginosis or UTI. Bacterial vaginosis and asymptomatic UTI both pose risk for mother and fetus. Early diagnosis and treatment can save the life of both. The present investigation was aimed to find out the magnitude of asymptomatic bacteriuria in pregnant women with noticeable bacterial vaginitis attending antenatal outpatient and inpatient of a tertiary care hospital and to identify the organisms causing it.
A total of 117 antenatal women from different age and parity groups with different gestational ages were included in the study. The samples were subjected to standard microbiological techniques for identification of microorganisms. While performing Per speculum examination, vaginal secretions were collected from the posterior fornix. Swabs from the posterior fornix were tested for pH using litmus paper. A wet mount and Gram smear was made and examined for the presence of bacteria, polymorphs and clue cells indicating bacterial vaginosis. Amsel's criteria and Nugent scoring system were applied for diagnosis of bacterial vaginosis. Antibiotic susceptibility of the isolated bacteria was performed using Kirby-Bauer method.
Bacterial vaginosis infection rate (62.3%) was common in the present study followed by asymptomatic UTI (n=60, 51%). It was also observed that asymptomatic urinary tract infection (UTI) with Bacterial vaginosis prevalent rate was 49 (41.8%) in the current study.
Bacterial vaginosis was more common than asymptomatic bacteriuria in pregnant women. It is recommended that antenatal health care facilities should incorporate screening of vaginitis among pregnant women to prevent the complications of pregnancy. And those women with Bacterial vaginosis should be screened for UTI. Proper use of antibiotics should be encouraged, abuse of antibiotics should be in check.
与细菌性阴道病或尿路感染患者相比，孕妇中细菌性阴道病与尿路感染之间的关联风险更高。细菌性阴道病和无症状性尿路感染均对母亲和胎儿构成风险。早期诊断和治疗可挽救二者的生命。本研究旨在查明在一家三级护理医院的产前门诊和住院部就诊的患有明显细菌性阴道炎的孕妇中无症状菌尿的发生率，并确定引起无症状菌尿的病原体。
本研究共纳入117名来自不同年龄、胎次组且具有不同孕周的孕妇。样本采用标准微生物学技术进行微生物鉴定。在进行窥器检查时，从阴道后穹窿采集阴道分泌物。用石蕊试纸检测后穹窿拭子的pH值。制作湿片和革兰氏涂片并检查是否存在指示细菌性阴道病的细菌、多形核白细胞和线索细胞。采用阿姆斯勒标准和纽金特评分系统诊断细菌性阴道病。使用 Kirby-Bauer 法对分离出的细菌进行药敏试验。
在本研究中，细菌性阴道病感染率（62.3%）较为常见，其次是无症状性尿路感染（n = 60，51%）。还观察到，在本研究中，伴有细菌性阴道病的无症状性尿路感染发生率为49例（41.8%）。
在孕妇中，细菌性阴道病比无症状菌尿更为常见。建议产前保健机构应将孕妇阴道炎筛查纳入其中，以预防妊娠并发症。对于患有细菌性阴道病的女性，应进行尿路感染筛查。应鼓励合理使用抗生素，抑制抗生素滥用。
