前列腺癌患者 PSA 为 1ng/ml，18F-氟丁氨酸 PET/CT 成像显示孤立性阴茎转移。

Solitary Penile Metastasis of Prostate Cancer on 18F-Fluciclovine PET/CT Imaging in a Patient With PSA of 1 ng/mL.

机构信息

From the Department of Radiology, University of Minnesota, Minneapolis, MN.

出版信息

Clin Nucl Med. 2020 May;45(5):389-391. doi: 10.1097/RLU.0000000000002987.

Abstract

An 85-year-old asymptomatic man with suspected biochemical recurrence of prostate cancer underwent an F-fluciclovine PET/CT scan, which revealed a solitary suspicious tracer uptake in the dorsal right corporal body of the proximal pendulous penis. The patient underwent ultrasound-guided fine-needle aspiration of the penile lesion, which revealed metastatic prostate cancer. The patient had definitive external beam radiation therapy 3 years before the examination. At the time of scan, the prostatic-specific antigen (PSA) was only 1.0 ng/mL, although the PSA doubling time was 2.6 months. It is unusual to detect a solitary penile metastasis in a patient with a low level of PSA.

摘要

一位 85 岁无症状男性，疑似前列腺癌生化复发，行 F-氟代脱氧葡萄糖（fluciclovine） PET/CT 扫描，显示阴茎悬垂部右侧背侧近段单一可疑示踪剂摄取。患者行超声引导下阴茎病变细针抽吸活检，结果显示为转移性前列腺癌。患者在检查前 3 年曾行根治性外照射放疗。扫描时，前列腺特异性抗原（PSA）仅为 1.0ng/mL，尽管 PSA 倍增时间为 2.6 个月。在 PSA 水平较低的患者中检测到单一阴茎转移较为罕见。