From the Department of Neonatology, Ber Jerbai Wadia Hospital for Children.
Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, India.
Clin Nucl Med. 2020 May;45(5):412-413. doi: 10.1097/RLU.0000000000002970.
A 4-day-old female neonate with raised cord blood thyroid-stimulating hormone (127 μIU/mL) underwent Tc thyroid scan to rule out thyroid dysgenesis. The images revealed midline focus of lingual thyroid as the only functioning thyroid tissue. In addition, bilateral focal and symmetrical breast uptake was seen without clinically palpable breast nodule on either side. Transplacental transfer of maternal hormones leading to stimulation of neonatal breasts explains this unusual scan finding. One should be aware of this rare pattern of focal breast uptake in Tc-pertechnetate scan in neonates with congenital hypothyroidism to avoid scan misinterpretation.
一名 4 天大的女婴,脐带血促甲状腺激素升高(127μIU/mL),行 Tc 甲状腺扫描以排除甲状腺发育不良。图像显示舌甲状腺的中线焦点是唯一有功能的甲状腺组织。此外,双侧出现局灶性和对称性乳腺摄取,两侧均无临床可触及的乳腺结节。母体激素的胎盘转移导致新生儿乳腺刺激,解释了这种异常扫描结果。对于先天性甲状腺功能减退症的新生儿,应注意 Tc 高锝酸盐扫描中这种罕见的局灶性乳腺摄取模式,以避免扫描误判。