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耳梅毒:文献复习。

Otosyphilis: A Review of the Literature.

机构信息

Washington State University, Spokane.

Department of Neurology, University of Washington, Seattle, WA.

出版信息

Sex Transm Dis. 2020 May;47(5):296-300. doi: 10.1097/OLQ.0000000000001155.

DOI:10.1097/OLQ.0000000000001155
PMID:32149965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8530448/
Abstract

The number of cases of syphilis has increased in the United States and in many high-income nations. Otosyphilis is a less recognized complication of syphilis that can lead to irreversible sensorineural hearing loss. Different pathophysiological mechanisms have been proposed to explain hearing loss in otosyphilis. We review the literature on otosyphilis in adults and propose the need for future work in this field to identify better ways to diagnose, treat, and manage this disease. Patients with syphilis should be screened routinely for hearing loss, and all patients with new, sudden, or fluctuating sensorineural hearing loss should be evaluated for syphilis.

摘要

梅毒病例在美国和许多高收入国家都有所增加。耳梅毒是梅毒较不被识别的并发症,可导致不可逆转的感音神经性听力损失。已经提出了不同的病理生理机制来解释耳梅毒中的听力损失。我们回顾了成人耳梅毒的文献,并提出需要在这一领域开展未来的工作,以确定更好的方法来诊断、治疗和管理这种疾病。患有梅毒的患者应常规筛查听力损失,所有患有新发、突发性或波动性感音神经性听力损失的患者均应评估是否患有梅毒。

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Otosyphilis: A Review of the Literature.耳梅毒:文献复习。
Sex Transm Dis. 2020 May;47(5):296-300. doi: 10.1097/OLQ.0000000000001155.
2
Sensorineural hearing loss due to secondary syphilis.二期梅毒所致感音神经性听力损失
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Cureus. 2025 Jan 12;17(1):e77338. doi: 10.7759/cureus.77338. eCollection 2025 Jan.
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A rare case report of bilateral vestibulopathy due to otosyphilis.一例罕见的耳梅毒引起的双侧前庭病报告。
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All Eyes and Ears: A Case of Neurosyphilis Presenting With Simultaneous Ocular and Otic Involvement.全感官受累:一例同时累及眼和耳的神经梅毒病例。
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BMC Public Health. 2023 Apr 24;23(1):754. doi: 10.1186/s12889-023-15510-4.
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Otosyphilis: A rare case of reversible hearing loss in a young man with secondary syphilis.耳梅毒:一名患有二期梅毒的年轻男性出现罕见的可逆性听力损失病例。
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本文引用的文献

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Neurosyphilis Treatment Outcomes After Intravenous Penicillin G Versus Intramuscular Procaine Penicillin Plus Oral Probenecid.神经梅毒经静脉注射青霉素 G 与肌肉注射普鲁卡因青霉素加口服丙磺舒治疗的转归。
Clin Infect Dis. 2020 Jul 11;71(2):267-273. doi: 10.1093/cid/ciz795.
2
Clinical Practice Guideline: Sudden Hearing Loss (Update).临床实践指南:突发性聋(更新)。
Otolaryngol Head Neck Surg. 2019 Aug;161(1_suppl):S1-S45. doi: 10.1177/0194599819859885.
3
Otosyphilis: Resurgence of an Old Disease.耳梅毒:一种古老疾病的再度流行
Laryngoscope. 2019 Jul;129(7):1680-1684. doi: 10.1002/lary.27635. Epub 2018 Dec 28.
4
How Well Do Neurologic Symptoms Identify Individuals With Neurosyphilis?神经症状能很好地识别神经梅毒患者吗?
Clin Infect Dis. 2018 Jan 18;66(3):363-367. doi: 10.1093/cid/cix799.
5
Prevalence Estimates of Complicated Syphilis.复杂梅毒的患病率估计
Sex Transm Dis. 2015 Dec;42(12):702-4. doi: 10.1097/OLQ.0000000000000368.
6
Toll-like receptor polymorphisms are associated with increased neurosyphilis risk.Toll样受体基因多态性与神经梅毒风险增加有关。
Sex Transm Dis. 2014 Jul;41(7):440-6. doi: 10.1097/OLQ.0000000000000149.
7
Unilateral sudden hearing loss due to otosyphilis.耳梅毒导致的单侧突发性听力损失。
Clin Pract. 2011 Dec 2;1(4):e133. doi: 10.4081/cp.2011.e133. eCollection 2011 Sep 28.
8
Computed tomography features of luetic osteitis (otosyphilis) of the temporal bone.颞骨梅毒性骨炎(耳梅毒)的计算机断层扫描特征。
J Laryngol Otol. 2014 Feb;128(2):185-8. doi: 10.1017/S0022215113003575. Epub 2014 Jan 30.
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Bilateral temporal bone otosyphilis.双侧颞骨耳梅毒
Otol Neurotol. 2014 Feb;35(2):e90-1. doi: 10.1097/MAO.0b013e3182a3603f.
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Cochleovestibular Deficit as First Manifestation of Syphilis in a HIV-Infected Patient.耳蜗前庭功能障碍作为一名HIV感染患者梅毒的首发表现
Case Rep Neurol. 2013 Mar 29;5(1):62-7. doi: 10.1159/000350574. Print 2013 Jan.