From the Department of Pediatrics.
Saint Louis University School of Medicine.
Pediatr Emerg Care. 2021 Dec 1;37(12):e1468-e1472. doi: 10.1097/PEC.0000000000002081.
This study aimed to determine if the 2016 clinical practice guidelines regarding brief resolved unexplained events (BRUE) impacted our institutional approach to infants with BRUE. We sought to determine the statement's impact on admission rates, emergency department (ED) length of stay, and return ED visits or readmissions.
We conducted a retrospective chart review of patients who presented to the ED at a tertiary pediatric hospital from January 2014 to June 2019. Diagnostic workup (laboratory testing, imaging, monitoring) in the ED was recorded. Cohorts of patients presenting pre- and post-2016 guideline were compared using χ2 and t tests. Subanalysis of higher-risk and lower-risk infant groups was also performed.
The demographics of the 2 cohorts were not significantly different. Comparison showed significant reductions in invasive testing after the guideline, both overall (P = 0.005), and specifically regarding comprehensive metabolic panel, blood culture, urine culture, and chest x-ray. Infants meeting higher-risk criteria also showed decreases in invasive testing (P = 0.02). Admission to the hospital and ED lengths of stay decreased in the post-American Academy of Pediatrics statement cohort (P < 0.001 and P = 0.007, respectively). There were no increases in readmissions or repeat ED visits.
This study revealed significant reduction in invasive testing, shorter lengths of ED stays, and lower admission rates at a tertiary care children's hospital after the release of the American Academy of Pediatrics BRUE guideline with no increase in return ED visits or readmissions.
本研究旨在确定 2016 年关于短暂性不明原因严重事件(BRUE)的临床实践指南是否影响了我们机构对 BRUE 婴儿的处理方式。我们旨在确定该指南对入院率、急诊科(ED)住院时间以及 ED 复诊或再入院的影响。
我们对 2014 年 1 月至 2019 年 6 月在一家三级儿科医院急诊科就诊的患者进行了回顾性病历审查。记录了急诊科的诊断性检查(实验室检查、影像学检查、监测)。使用 χ2 检验和 t 检验比较了指南发布前后的患者队列。还对高风险和低风险婴儿组进行了亚组分析。
两个队列的患者人口统计学特征无显著差异。比较显示,指南发布后,包括全面代谢谱、血培养、尿培养和胸部 X 线在内的侵入性检查显著减少(均 P = 0.005)。符合高风险标准的婴儿的侵入性检查也有所减少(P = 0.02)。发布美国儿科学会声明后,住院和 ED 住院时间均缩短(均 P < 0.001 和 P = 0.007)。再入院或再次 ED 就诊无增加。
本研究表明,在发布美国儿科学会 BRUE 指南后,三级儿童保健医院的侵入性检查减少,ED 住院时间缩短,入院率降低,而 ED 复诊或再入院率无增加。