Zhang Ying, Lou Li-Li, Shi Xiao-Dong, Lu Sha-Sha, Zhang Li-Xia, Huang Xu, Ji Hui-Fan, Li Xu, Guo Xiao-Lin
Department of Hepatology, The First Hospital of Jilin University, Chang chun, China.
Medicine (Baltimore). 2020 Mar;99(10):e19450. doi: 10.1097/MD.0000000000019450.
Myelodysplastic syndrome (MDS) can be complicated with Crohn disease (CD). Irritable bowel disease (IBD) associated with MDS has already been reported in the past; however, hematopoietic stem cell transplantation (HSCT) is rarely performed. Herein, we report a case of CD with MDS for HSCT.
A 41-year-old man was hospitalized due to abdominal pain and intermittent fever for 40 days. Two years later, he was readmitted due to abdominal pain and diarrhea with fever for 10 days.
Symptoms, laboratory examinations, and imaging findings of the patient were indicative of CD complicated with MDS.
An allogeneic HSCT was performed.
He died of severe lung infection 125 days post-transplantation.
The number of cases of CD combined with MDS remains insufficient, and no consensus opinions are available to date. Hence, HSCT is a very potential treatment method. Additional experiences are needed to determine its effectiveness.
骨髓增生异常综合征（MDS）可并发克罗恩病（CD）。过去已有MDS相关的炎症性肠病（IBD）的报道；然而，很少进行造血干细胞移植（HSCT）。在此，我们报告1例接受HSCT治疗的合并MDS的CD患者。
一名41岁男性因腹痛和间歇性发热40天入院。两年后，他因腹痛、腹泻伴发热10天再次入院。
患者的症状、实验室检查及影像学表现提示为合并MDS的CD。
进行了异基因HSCT。
移植后125天，患者死于严重肺部感染。
CD合并MDS的病例数量仍然不足，目前尚无共识性意见。因此，HSCT是一种非常有潜力的治疗方法。需要更多经验来确定其有效性。
