Prevention and Implementation Group, Section of Early Detection and Prevention, International Agency for Research on Cancer, Lyon, France.
Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.
Int J Cancer. 2020 Sep 15;147(6):1638-1648. doi: 10.1002/ijc.32956. Epub 2020 Apr 9.
In May 2018, the World Health Organization (WHO) called for the elimination of cervical cancer. To monitor this initiative, we examined cervical cancer incidence and mortality in the Latin America and Caribbean (LAC) region using GLOBOCAN 2018, Cancer Incidence in Five Continents Series, and the WHO Mortality Database. We estimated the number of cases and age-standardized rates (ASRs) for cervical cancer incidence and mortality for 2018. We also presented the ASRs for recorded cervical cancer incidence from the period 2008 to 2012. We calculated annual rates and analyzed trends in cervical cancer incidence and mortality for all ages combined and for the following age groups: 0-29, 30-49, 50-64 and 65+. Finally, we calculated the estimated average annual percentage change in incidence and mortality rates for the past 10 years. In 2018, an estimated 56,000 new cervical cancer cases and 28,000 cervical cancer deaths occurred among women in LAC with great variations between subregions and countries/territories. Overall, trends in cervical cancer incidence and mortality have decreased over the past decade; however, the rates are still above the elimination threshold of 4 per 100,000 in most LAC countries/territories. Despite the encouraging trends observed, achieving the elimination of cervical cancer in the region still requests substantial political commitment and economic effort. Population-based cancer registries are critical in monitoring the elimination initiative.
2018 年 5 月，世界卫生组织（WHO）呼吁消除宫颈癌。为了监测这一倡议，我们使用 GLOBOCAN 2018、《五大洲癌症发病率》系列和世卫组织死亡率数据库，研究了拉丁美洲和加勒比（LAC）地区的宫颈癌发病率和死亡率。我们估算了 2018 年宫颈癌发病和死亡的病例数和年龄标准化率（ASR）。我们还展示了 2008 年至 2012 年期间记录的宫颈癌发病 ASR。我们计算了所有年龄段以及以下年龄段的宫颈癌发病率和死亡率的年率，并分析了其趋势：0-29 岁、30-49 岁、50-64 岁和 65 岁及以上。最后，我们计算了过去 10 年发病率和死亡率的估计年均变化百分比。2018 年，LAC 地区约有 5.6 万名新确诊宫颈癌病例和 2.8 万名宫颈癌死亡病例，各次区域和国家/地区之间存在很大差异。总体而言，过去十年中宫颈癌发病率和死亡率呈下降趋势；然而，在大多数 LAC 国家/地区，这一比率仍高于消除宫颈癌的 4/10 万的阈值。尽管观察到令人鼓舞的趋势，但要在该地区实现消除宫颈癌的目标，仍然需要大量的政治承诺和经济投入。基于人群的癌症登记处对于监测消除倡议至关重要。
