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在比达联邦医疗中心普通门诊就诊的6个月至14岁儿童中特应性皮炎的患病率及模式

Prevalence and Pattern of Atopic Dermatitis among Children Aged 6 Months to 14 Years seen in General Out-Patient Clinic of Federal Medical Centre, Bida.

作者信息

Wey G D, Adefemi S A, Amao E A

机构信息

Department of Family Medicine, Federal Medical Centre,Bida,Nigeria.

Shalom Medical Centre, Ogbomoso, Nigeria.

出版信息

West Afr J Med. 2020 Apr-Jun;37(2):124-130.

Abstract

BACKGROUND

Atopic dermatitis (AD) is a chronic, inflammatory, itchy skin condition that develops in early childhood in the majority of cases. It is typically an episodic disease of exacerbations and remissions, except for severe cases where it may be continuous. In children younger than one, the face and extensor surfaces of the hands and legs are typically involved, and in some case the trunk as well. The aim of this study was to determine the prevalence, pattern, and sites of atopic dermatitis among children aged 6 months to 14 years, as well as document the full blood count picture with emphasis on the eosinophil count as a correlate in predicting atopic dermatitis.

METHODS

This was a descriptive cross-sectional study of 490 eligible children recruited using the systematic random sampling technique. The data collected was analyzed using statistical package for social sciences, version 22 (SPSS 22 Chicago, Illinois, USA).

RESULTS

The prevalence of AD from this study was 9.8% using the Hanifin and Rajka criteria, with the age group <5 years having the highest prevalence of 47.9% and it was more common in males than in females 64.6% and 35.4% respectively. The commonest site of affectation was the face and extensor surface (100.0%; 95.8% respectively). In terms of the severity of AD using the TIS score, majority were in the moderate category (81.3%). Mean Eosinophil count was 8.75% ±5.90. There was a statistical significant association between absence of AD and elevated absolute eosinophil count (P=0.015).

CONCLUSION

The study highlights that the prevalence of atopic dermatitis among children 6 months to 14 years based on major Hanifin and Rajka Criteria is 9.8%. Individuals with AD are unlikely to have elevated absolute eosinophil count.

摘要

背景

特应性皮炎(AD)是一种慢性炎症性瘙痒性皮肤病,大多数病例在儿童早期发病。除严重病例可能持续存在外,它通常是一种发作与缓解交替的疾病。对于1岁以下儿童,面部以及手和腿的伸侧通常受累,在某些情况下躯干也会受累。本研究的目的是确定6个月至14岁儿童特应性皮炎的患病率、模式和受累部位,并记录全血细胞计数情况,重点关注嗜酸性粒细胞计数与预测特应性皮炎的相关性。

方法

这是一项描述性横断面研究,采用系统随机抽样技术招募了490名符合条件的儿童。收集的数据使用社会科学统计软件包第22版(SPSS 22,美国伊利诺伊州芝加哥)进行分析。

结果

根据汉内芬和拉伊卡标准,本研究中AD的患病率为9.8%,<5岁年龄组患病率最高,为47.9%,男性比女性更常见,分别为64.6%和35.4%。最常受累的部位是面部和伸侧(分别为100.0%;95.8%)。根据TIS评分,AD的严重程度方面,大多数属于中度(81.3%)。嗜酸性粒细胞平均计数为8.75%±5.90。无AD与绝对嗜酸性粒细胞计数升高之间存在统计学显著关联(P = 0.015)。

结论

该研究强调,根据主要的汉内芬和拉伊卡标准,6个月至14岁儿童特应性皮炎的患病率为9.8%。患有AD的个体不太可能有升高的绝对嗜酸性粒细胞计数。

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