Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA; Psychosocial Research Program, Butler Hospital, Providence, RI, USA.
Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA; Psychosocial Research Program, Butler Hospital, Providence, RI, USA; Behavioral Medicine & Addiction Research, Butler Hospital, Providen,ce, RI, USA.
Contemp Clin Trials. 2020 Apr;91:105974. doi: 10.1016/j.cct.2020.105974. Epub 2020 Mar 7.
Regular engagement in physical activity decreases risks for many chronic conditions, and may also improve depression symptoms. However, rates of physical activity and adherence to exercise interventions remain low among depressed individuals relative to non-depressed individuals.
This is a study protocol for Project MOVE. This study is a theoretically-driven, 3-arm randomized controlled trial for increasing physical activity with depressed adults. Each successive arm includes an added component that may serve to increase and maintain physical activity. The arms are: 1) Brief advice (BA) to exercise alone (minimal treatment control condition); 2) BA + supervised and home-based exercise (SHE) + health education (HE; serves as contact control for CBEX); and 3) BA + SHE +cognitive-behavioral sessions focused on increasing and maintaining exercise (CBEX). The target sample size is 240. Assessments are conducted at baseline, Month 1.5, end of intervention (month 3), and at 6 and 9 months. The primary outcome is minutes of moderate-to-vigorous physical activity, assessed via an accelerometer. Secondary outcomes include cardiorespiratory fitness, body composition, and depression, and maintenance of moderate-vigorous physical activity through 6 and 9 month follow-ups. Mediators and moderators derived from behavior change theories, including the Health Behavior Model, Self-Determination Theory, and Social Ecological Theory, will be examined.
Project MOVE is designed to test primarily whether both a structured exercise program (SHE) and a cognitive-behavioral group (CBEX) increase physical activity in depressed adults during both a 3-month intervention period, and during the 6-months that follow.
定期进行身体活动可以降低许多慢性疾病的风险，也可能改善抑郁症状。然而，与非抑郁个体相比，抑郁个体的身体活动率和对运动干预的依从性仍然较低。
这是 Project MOVE 的研究方案。这是一项针对抑郁成年人增加身体活动的理论驱动、3 臂随机对照试验。每个连续的手臂都包含一个附加的组件，可能有助于增加和维持身体活动。这些手臂是：1）单独锻炼的简要建议（BA）（最低限度的治疗控制条件）；2）BA+监督和家庭锻炼（SHE）+健康教育（HE；作为 CBEX 的联系控制）；3）BA+SHE+以增加和维持锻炼为重点的认知行为课程（CBEX）。目标样本量为 240 人。评估在基线、第 1.5 个月、干预结束（第 3 个月）以及第 6 个月和第 9 个月进行。主要结果是通过加速度计评估的中度至剧烈体力活动分钟数。次要结果包括心肺健康、身体成分和抑郁，以及通过 6 个月和 9 个月的随访来维持中度至剧烈体力活动。将从行为改变理论（包括健康行为模型、自我决定理论和社会生态理论）中得出的中介和调节因素进行检查。
Project MOVE 的设计主要是测试结构锻炼计划（SHE）和认知行为小组（CBEX）是否都能在 3 个月的干预期内以及随后的 6 个月内增加抑郁成年人的身体活动。
