Hetea Andreea, Cosconel Cristiana, Stanescu Ana Alexandra Maria, Simionescu Anca A
Filantropia Hospital, Department of obstetrics and Gynecology, Bucharest, Romania.
"Carol Davila" University of Medicine and Pharmacy, Department of Foreign Languages, Bucharest, Romania.
Maedica (Bucur). 2019 Dec;14(4):397-401. doi: 10.26574/maedica.2019.14.4.397.
Although often difficult to diagnose, the use of psychoactive drugs during pregnancy has become a commonly encountered occurrence. The present article aims to clarify the effects of alcohol, tobacco, narcotics, antidepressants, stimulants, halucinogenes and canabioids consumption on pregnancy and the newborn. There are differences within the types of drugs consumption: use/abuse/addiction of psychoactive medication during pregnancy. The fetal alcohol syndrome occurs in case of alcohol exposure during pregnancy. It is characterized by fetal alcohol spectrum disorders, lower neurobehavioral scores, mental retardation, heart defects and special facial features. Heroin consumption can lead to prematurity, intrauterine growth restriction, stillbirth or to hemorrhage in the third trimester of pregnancy; it can be associated with malnutrition, venereal diseases, hepatitis, pulmonary complications or preeclampsia. During pregnancy, the effects of cocaine use include cardiovascular complications, neurological complications, infections (sexually transmitted diseases - gonorrhea, Chlamydia infections, syphilis, HPV), obstetric complications (premature birth, fetal death, abruptio placentae). In the fetus, the consequences of cocaine consumption can trigger limb defects, urinary tract malformations, fetal microcephaly, perinatal cerebral infarctions. In conclusion, identifying the profile of pregnant drug users can trigger better care both for the mother, and for the fetus; information and prevention campaigns should provide data on their adverse effects on pregnancy.
尽管孕期使用精神活性药物往往难以诊断,但这种情况已屡见不鲜。本文旨在阐明饮酒、吸烟、使用麻醉药品、抗抑郁药、兴奋剂、致幻剂和大麻类物质对妊娠及新生儿的影响。药物使用类型存在差异:孕期使用/滥用/成瘾精神活性药物。孕期接触酒精会导致胎儿酒精综合征。其特征为胎儿酒精谱系障碍、神经行为评分降低、智力迟钝、心脏缺陷及特殊面部特征。使用海洛因可导致早产、子宫内生长受限、死产或妊娠晚期出血;还可能伴有营养不良、性病、肝炎、肺部并发症或先兆子痫。孕期使用可卡因的影响包括心血管并发症、神经并发症、感染(性传播疾病——淋病、衣原体感染、梅毒、人乳头瘤病毒)、产科并发症(早产、胎儿死亡、胎盘早剥)。对胎儿而言,使用可卡因的后果可能引发肢体缺陷、泌尿系统畸形、胎儿小头畸形、围产期脑梗死。总之,识别孕期吸毒者的情况有助于为母亲和胎儿提供更好的护理;宣传和预防活动应提供有关其对妊娠不良影响的数据。