Adib-Rad Hajar, Basirat Zahra, Faramarzi Mahbobeh, Mostafazadeh Amrollah, Bijani Ali, Bandpy Marmar Firozpour
Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Department of Immunology and Microbiology, Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
J Educ Health Promot. 2020 Jan 30;9:14. doi: 10.4103/jehp.jehp_381_19. eCollection 2020.
Postpartum period and recurrent abortion are stressful conditions that affect women's mental health. Stress and depression lead to the release of stress biomarkers that may be dangerous for the mother and fetus. The aim of this study was to determine stress in the after recurrent pregnancy loss (RPL) and normal vaginal delivery (NVD) in the north of Iran.
This case-control study was done on forty women with NVD and forty women with RPL. Stress was measured through measuring serum cortisol, Perceived Stress Scale-14 (PSS-14), and the revised version of the Symptom Checklist-90 (SCL-90-R). Data were analyzed using the Statistical Package for the Social Sciences (SPSS) 22.0 software. Chi-square test, independent-samples -test, Mann-Whitney U-test, and Pearson correlation were used to analyze the data.
Findings showed that nonpregnant healthy women had significantly higher cortisol level than RPL women (mean ± standard deviation [SD]: 155.80 ± 84.97 ng/ml and 126.02 ± 50.44 ng/ml, < 0.011), respectively. Furthermore, they had higher PSS-14 and SCL-90 scores than PRL women (mean ± SD: 25.87 ± 7.48 and 25.5 ± 9.19, = 0.745, and mean ± SD: 1.27±0.63 and 1.20 ± 0.53, = 0.624), respectively.
High levels of cortisol reflect the acute stress caused by the care of the baby in women. Therefore, social support for the pregnant woman by the health-care team is an essential factor for reducing postpartum depression.
产后阶段和复发性流产是影响女性心理健康的压力性状况。压力和抑郁会导致应激生物标志物的释放，这可能对母亲和胎儿都有危险。本研究的目的是确定伊朗北部复发性妊娠丢失（RPL）和正常阴道分娩（NVD）后的压力情况。
本病例对照研究对40名正常阴道分娩的女性和40名复发性妊娠丢失的女性进行。通过测量血清皮质醇、感知压力量表-14（PSS-14）和症状自评量表90修订版（SCL-90-R）来测量压力。使用社会科学统计软件包（SPSS）22.0软件对数据进行分析。采用卡方检验、独立样本t检验、曼-惠特尼U检验和皮尔逊相关性分析数据。
研究结果显示，未怀孕的健康女性的皮质醇水平显著高于复发性妊娠丢失的女性（均值±标准差[SD]：分别为155.80±84.97 ng/ml和126.02±50.44 ng/ml，P<0.011）。此外，她们的PSS-14和SCL-90得分也高于复发性妊娠丢失的女性（均值±标准差：分别为25.87±7.48和25.5±9.19，P = 0.745，以及均值±标准差：1.27±0.63和1.20±0.53，P = 0.624）。
高水平的皮质醇反映了女性照顾婴儿所引起的急性压力。因此，医疗团队对孕妇的社会支持是减少产后抑郁的一个重要因素。
