Department of Obstetrics and Gynecology, "Victor Babes" University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Int J Environ Res Public Health. 2023 Jan 10;20(2):1208. doi: 10.3390/ijerph20021208.
Recurrent pregnancy loss (RPL) is one of the most challenging and difficult areas of reproductive treatment due to the immense emotional suffering inflicted on families and couples affected by RPL. As a result, it is predicted that couples experiencing recurrent pregnancy loss would have an increase in marital problems, stress levels, and anxiety, preventing them from achieving their family goals. The current cross-sectional study aimed to target pregnant women with thrombophilia with a history of RPL to observe their intimacy problems, stress levels, and couple satisfaction by completing a series of digital questionnaires. These patients were considered as the reference group, while the control group was formed by other women with thrombophilia and a history of RPL who eventually achieved pregnancy and gave birth. A total of 238 complete questionnaires were recorded (157 in the reference group and 81 in the control group). It was observed that women in the reference group who did not give birth had a significantly higher proportion of three or more pregnancy attempts (54.1% vs. 39.5%) and a significantly higher proportion of three more pregnancy losses (68.8% vs. 55.6%). It was observed that patients in the reference group were more likely to be emotion-oriented (42.7% vs. 27.2%). Also, women in the reference group had higher levels of dissatisfaction and lower levels of self-acceptance, pleasure, and marital quality scores. The total SII and DSCS scores were significantly lower than women with thrombophilia with a history of RPL who eventually gave birth. Women from the reference group had significantly greater intimacy problems and stress levels while having lower openness scores and self-esteem scores than women in the control group. It is possible that women with thrombophilia and recurrent pregnancy loss are more dissatisfied with their marriages than those who subsequently had one child. Since the financial status of those who achieved pregnancy was observed to be higher, it is likely that they achieved pregnancy by ART interventions, as they reported in questionnaires. It is important to target families afflicted by thrombophilia and other reasons for infertility to ease their access to ART therapies. By achieving their objectives, affected families will minimize dissatisfaction, divorce rates, and stress.
复发性流产（RPL）是生殖治疗中最具挑战性和困难的领域之一，因为 RPL 给受影响的家庭和夫妇带来了巨大的情感痛苦。因此，预计反复妊娠丢失的夫妇会增加婚姻问题、压力水平和焦虑，从而阻止他们实现家庭目标。本横断面研究旨在针对有 RPL 病史的血栓形成倾向孕妇，通过完成一系列数字问卷来观察她们的亲密问题、压力水平和夫妻满意度。这些患者被视为参考组，而对照组由其他有血栓形成倾向和 RPL 病史但最终怀孕并分娩的妇女组成。共记录了 238 份完整的问卷（参考组 157 份，对照组 81 份）。结果观察到，未分娩的参考组妇女有更高比例的三次或更多次妊娠尝试（54.1%比 39.5%）和三次以上妊娠丢失（68.8%比 55.6%）。观察到参考组患者更倾向于情绪导向（42.7%比 27.2%）。此外，参考组妇女的不满程度更高，自我接纳、愉悦和婚姻质量评分较低。总 SII 和 DSCS 评分明显低于最终分娩的有 RPL 病史的血栓形成倾向妇女。参考组妇女的亲密问题和压力水平明显更大，而开放性和自尊心评分明显低于对照组妇女。有血栓形成倾向和复发性流产的妇女比随后有一个孩子的妇女对婚姻更不满意是有可能的。由于观察到那些怀孕的人的经济状况更高，他们可能通过 ART 干预怀孕，正如他们在问卷中报告的那样。重要的是要为受血栓形成和其他不孕原因影响的家庭提供便利，使他们能够获得 ART 治疗。通过实现他们的目标，受影响的家庭将最大限度地减少不满、离婚率和压力。
