血清样本中毛霉目 DNA 的检测对毛霉病的早期诊断。
Mucorales DNA detection in serum specimens for early diagnosis of mucormycosis.
机构信息
Laboratoire de Parasitologie et Mycologie, Hôpital de La Cavale Blanche, CHU de Brest, Brest, France; Groupe d'Etude des Interactions Hôte-Pathogène (GEIHP; EA 3142), Université de Bretagne Occidentale-Université d'Angers, Brest, France.
Service d'Hématologie Clinique, Hôpital Morvan, CHU de Brest, Brest, France.
出版信息
Diagn Microbiol Infect Dis. 2020 Jun;97(2):115004. doi: 10.1016/j.diagmicrobio.2020.115004. Epub 2020 Jan 29.
We report a case of pulmonary mucormycosis in a patient with T-cell acute lymphoblastic leukemia. The diagnosis of mucormycosis was initially based on mycological examination of a pulmonary specimen. However, we describe how it could have been made 2 months earlier using polymerase chain reaction assays targeting Mucorales species on serum specimens.
我们报告了一例 T 细胞急性淋巴细胞白血病患者的肺毛霉病。毛霉病的诊断最初基于肺部标本的真菌学检查。然而，我们描述了如何在 2 个月前使用针对血清标本中毛霉目的聚合酶链反应检测来更早地做出诊断。
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