Motegi Daisuke, Ichikawa Hiroshi, Kano Yosuke, Hanyu Takaaki, Ishikawa Takashi, Usui Kenji, Sakai Takeshi, Hirose Yuki, Miura Kohei, Nagahashi Masayuki, Shimada Yoshifumi, Sakata Jun, Kobayashi Takashi, Kameyama Hitoshi, Wakai Toshifumi
Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences.
Gan To Kagaku Ryoho. 2019 Dec;46(13):2192-2194.
A 66-year-old man with middle thoracic esophageal squamous cell carcinoma with supraclavicular lymph node metastasis visited our hospital. He underwent 3 courses of preoperative chemotherapy with docetaxel, cisplatin, and 5-FU(DCF)with a clinically-determined partial response. Minimally-invasive esophagectomy with 3-fieldlymphad enectomy was subsequently performed. Histopathologic examination revealedno viable tumor cells in the resectedesophagus andsupraclavicular lymph node. DCF is a promising preoperative chemotherapy regimen for locally advanced esophageal cancer because of its higher complete response rate comparedto that for cisplatin plus 5-FU.
一名66岁男性，患有胸段中段食管鳞状细胞癌并伴有锁骨上淋巴结转移，前来我院就诊。他接受了3个疗程的术前化疗，使用多西他赛、顺铂和5-氟尿嘧啶（DCF方案），临床判定为部分缓解。随后进行了微创食管切除术及三野淋巴结清扫术。组织病理学检查显示，切除的食管和锁骨上淋巴结中未发现存活的肿瘤细胞。DCF方案是一种有前景的局部晚期食管癌术前化疗方案，因为与顺铂加5-氟尿嘧啶方案相比，其完全缓解率更高。
