Hirose Hajime, Yoshioka Shinichi, Mokutani Yukako, Takeda Masashi, Imamura Hiroki, Yoneda Naoki, Kidogami Shinya, Kishimoto Tomoya, Hashimoto Yasuji, Endo Shunji, Tamura Shigeyuki, Kodama Ken, Sasaki Yo
Dept. of Surgery, Yao Municipal Hospital.
Gan To Kagaku Ryoho. 2019 Dec;46(13):2267-2269.
In general, distant metastasis is uncommon in colorectal submucosal(SM)invasion without lymph node metastasis. We experienced an extremely rare case of synchronous pulmonary metastases for colon cancer in SM invasion. A man in his 70s was seen at the hospital for a positive fecal occult blood test. Colonoscopy revealed 3 lesions in the sigmoid colon and endoscopic mucosalresection revealed 2,000 mm SM invasion in all 3 lesions. Computed tomography showed no signs of distant lymph node or liver metastasis but showed small nodules in both lungs. Radical treatment included laparoscopic anterior resection with lymph node dissection. Histological examination showed no residual tumor in the colon and no lymph node metastasis. Two years after surgery, the number of lung nodules gradually increased and we performed partial resection of the left lung, which was diagnosed as pulmonary metastasis from colon cancer by histological examination. Therefore, we resected the opposite-side pulmonary metastases. The patient has exhibited no other signs of recurrence in the 2 years since the last operation.
一般来说,在无淋巴结转移的结直肠黏膜下(SM)浸润中,远处转移并不常见。我们遇到了一例极为罕见的在SM浸润的结肠癌中出现同步肺转移的病例。一名70多岁的男性因粪便潜血试验阳性到医院就诊。结肠镜检查发现乙状结肠有3个病变,内镜黏膜切除术显示所有3个病变均有2000毫米的SM浸润。计算机断层扫描显示无远处淋巴结或肝转移迹象,但双肺有小结节。根治性治疗包括腹腔镜前切除术及淋巴结清扫术。组织学检查显示结肠无残留肿瘤且无淋巴结转移。术后两年,肺结节数量逐渐增加,我们对左肺进行了部分切除术,组织学检查诊断为结肠癌肺转移。因此,我们切除了对侧肺转移灶。自上次手术以来的两年里,患者未出现其他复发迹象。