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德国传染病领域“明智选择”倡议的最新进展。

Update on the "Choosing Wisely" initiative in infectious diseases in Germany.

机构信息

LMU Klinikum, Stabsstelle Antibiotic Stewardship, Ludwig-Maximilians-University, Munich, Germany.

Division of Infectious Diseases, Department of Internal Medicine, University of Cologne, Cologne, Germany.

出版信息

Infection. 2020 Jun;48(3):317-321. doi: 10.1007/s15010-020-01400-z. Epub 2020 Mar 10.

DOI:10.1007/s15010-020-01400-z
PMID:32157610
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7256090/
Abstract

PURPOSE

The Choosing Wisely initiative is an international campaign addressing over- and underuse of diagnostic and therapeutic measures in infectious diseases among others. Since 2016, the German Society for Infectious Diseases (DGI) has constantly designed new items in this regard. Here we report the most recent recommendations.

METHODS

The recommendations of the DGI are part of the "Klug entscheiden" initiative of the German Society of Internal Medicine (DGIM). Topics for the new items were suggested by members of the DGI, checked for scientific evidence and consented within the DGI and the DGIM before publication.

RESULTS

The new recommendations are: (1) individuals with immune-suppression, advanced liver cirrhosis or renal insufficiency should receive a dual pneumococcal vaccination. (2) In case of positive blood cultures with Candida spp. thorough diagnostics and treatment should be initiated. (3) In case of suspected meningitis, adult patients should receive dexamethasone and antibiotics immediately after venipuncture for blood cultures and before potential imaging. (4) In case of suspected meningitis a CT scan before lumbar puncture should not be ordered-except for symptoms indicating high CSF pressure or focal brain pathology or in cases of severe immune-suppression. (5) In patients with suspected severe infections, a minimum of two pairs of blood cultures should be drawn using separate venipunctures prior to antibiotic therapy-regardless of body temperature. There is no need of a minimum time interval in between the blood draws.

CONCLUSION

Applying these new Choosing Wisely recommendations will increase patient safety and the value of health care.

摘要

目的

明智选择倡议是一项国际性运动,旨在解决传染病等领域中诊断和治疗措施的过度和不足使用问题。自 2016 年以来,德国传染病学会(DGI)一直在这方面不断设计新的项目。在此,我们报告最新的建议。

方法

DGI 的建议是德国内科医师学会(DGIM)“明智选择”倡议的一部分。新项目的主题由 DGI 成员提出,在发表之前,经过科学证据检查并在 DGI 和 DGIM 内部达成一致。

结果

新建议包括:(1)免疫抑制、晚期肝硬化或肾功能不全者应接受双重肺炎球菌疫苗接种。(2)血培养阳性的念珠菌属时,应进行彻底诊断和治疗。(3)疑似脑膜炎时,成年患者应在血培养静脉穿刺后立即接受地塞米松和抗生素治疗,然后再进行潜在的影像学检查。(4)疑似脑膜炎时,除非出现高脑脊液压力或局灶性脑病理或严重免疫抑制等症状,否则不应在腰椎穿刺前进行 CT 扫描。(5)疑似严重感染患者,在开始抗生素治疗前,应使用单独的静脉穿刺采集至少两对血培养 - 无论体温如何。两次采血之间不需要间隔最小时间。

结论

应用这些新的明智选择建议将提高患者安全性和医疗保健的价值。