Brooks John K, Jones Joyce L, Price Jeffery B
Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry, Baltimore, Maryland.
Department of Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Spec Care Dentist. 2020 May;40(3):298-302. doi: 10.1111/scd.12455. Epub 2020 Mar 11.
Although there appears to be an overall trend of diminishing oral manifestations of HIV infection, evidence is emerging on the increased incidence of concomitant parotid gland enlargement and xerostomia. Furthermore, several case narrations and a limited series have suggested a possible association of sialolithiasis with highly active antiretroviral therapy, mostly involving the parotid gland. The aim of this report is to present a patient with a giant sialolith of the submandibular gland following a 27-year intake of various antiretrovirals for HIV infection and review the relevant literature.