Grobet P, Duchesne B, Jaumotte M, Pepinster F, Gilon Y
Service de Chirurgie plastique et maxillo-faciale, CHU Liège, Belgique.
Service d'Ophtalmologie, CHU Liège, Belgique.
Rev Med Liege. 2020 Mar;75(3):164-170.
As the leading cause of blindness in the world, corneal diseases are second only to cataracts. However, the epidemiology of corneal disease is complex and includes a wide variety of infectious and inflammatory eye diseases (trachoma), immune sequelae (cicatricial pemphigoid on Lyell's disease) of after trauma (chemical burn). The general treatment for severe corneal disease is the corneal transplantation with penetrating keratoplasty. However, the failure of this treatment is virtually certain when the ocular surface is severely compromised. Keratoprosthesis is therefore the only viable option to restore vision in these patients. Only practiced by less than a dozen teams in the world, the osteo-odonto-keratoprosthesis (OOKP) is regularly practiced at the University Hospital of Liège, thanks to a close collaboration between the ophthalmology and maxillofacial surgery teams. Thanks to removal of a tooth and his bone support, patients suffering from bilateral dry eye following pathologies such as burns or cicatricial pemphigoid can benefit from this technique in order to recover an optimal visual acuity in a sustainable way.
作为全球失明的主要原因，角膜疾病仅次于白内障。然而，角膜疾病的流行病学情况复杂，涵盖了多种感染性和炎症性眼病（沙眼）、免疫后遗症（瘢痕性类天疱疮或莱尔病）以及外伤后（化学烧伤）的情况。严重角膜疾病的一般治疗方法是穿透性角膜移植术。然而，当眼表严重受损时，这种治疗几乎注定会失败。因此，角膜移植术是恢复这些患者视力的唯一可行选择。骨牙角膜移植术（OOKP）在全球只有不到十几个团队开展，由于列日大学医院眼科和颌面外科团队的密切合作，该手术在列日大学医院经常进行。得益于拔除一颗牙齿及其骨支撑结构，因烧伤或瘢痕性类天疱疮等病症而患有双侧干眼症的患者可以受益于这项技术，从而以可持续的方式恢复最佳视力。
