Manckoundia P, Mourey F
Service de Médecine Interne Gériatrie, Hôpital de Champmaillot CHU, Dijon, France.
INSERM U1093 Cognition, Action et Plasticité Sensorimotrice (CPAS), Université de Bourgogne, Dijon, France.
Rev Med Liege. 2020 Mar;75(3):180-184.
Psychomotor disadaptation syndrome (PDS) was first described by the Geriatrics School of Dijon (France), three decades ago, under the name «psychomotor regression syndrome». Over time, the original clinical features remained unchanged. However, progress has been made in its pathophysiology understanding and care, hence the new name, PDS, appeared in the 1990s. The PDS is also called sub-cortico-frontal dysfunction syndrome since the 2000s. It corresponds to a decompensation of posture, gait and psychomotor automatisms, related to an alteration of the postural and motor programming, which is a consequence of sub-cortico-frontal lesions. The clinical features of PDS associate backward disequilibrium, nonspecific gait disorders and neurological signs (akinesia, reactional hypertonia, impaired reactive postural responses and protective reactions, etc.). Psychological disorders of PDS are a fear of standing and walking in its acute form (the post-fall syndrome), or a bradyphrenia and anhedonia in its chronic form. The PDS occurrence results from the combination of three factors implicated in the reduction in functional reserves related to the alteration of the sub-cortico-frontal structures: ageing, chronic afflictions and acute situations, which induce a decrease in cerebral blood flow. The PDS management must be multidisciplinary, including the physician, the physiotherapist, the psychologist, nurses and care assistants.
精神运动适应不良综合征(PDS)最早由法国第戎老年病学派于三十年前以“精神运动衰退综合征”之名进行描述。随着时间推移,其最初的临床特征保持不变。然而,在对其病理生理学的理解和护理方面取得了进展,因此在20世纪90年代出现了新名称PDS。自21世纪以来,PDS也被称为皮质下额叶功能障碍综合征。它对应于姿势、步态和精神运动自动症的失代偿,与姿势和运动编程的改变有关,这是皮质下额叶病变的结果。PDS的临床特征包括向后失衡、非特异性步态障碍和神经学体征(运动不能、反应性张力亢进、反应性姿势反应和保护性反应受损等)。PDS的心理障碍在急性形式(跌倒后综合征)表现为对站立和行走的恐惧,在慢性形式表现为思维迟缓及快感缺失。PDS的发生是由与皮质下额叶结构改变相关的功能储备减少所涉及的三个因素共同作用导致的:衰老、慢性疾病和急性情况,这些因素会导致脑血流量减少。PDS的管理必须是多学科的,包括医生、物理治疗师、心理学家、护士和护理助理。