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慢性鼻-鼻窦炎中真菌性鼻窦炎的患病率及临床特征研究

A Study on the Prevalence and Clinical Features of Fungal Sinusitis in Chronic Rhinosinusitis.

作者信息

Shetty Sandeep, Chandrashekar Shilpa, Aggarwal Nitish

机构信息

Department of ENT, Head and Neck Surgery, JSS Academy of Higher Education and Research, Mysuru, Karnataka India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):117-122. doi: 10.1007/s12070-019-01769-w. Epub 2019 Dec 5.

DOI:10.1007/s12070-019-01769-w
PMID:32158667
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7040144/
Abstract

Chronic sinusitis is a common disorder worldwide a significant proportion of which is secondary to fungal aetiology contrary to popular belief that fungal sinusitis is a rare entity, more so in a country like India where warm moist climate in a number of states and ever rising incidence of diabetes mellitus gives the fungal organisms a perfect environment to grow. This study aims to find the incidence and clinical features of fungal rhinosinusitis in chronic rhinosinusitis reinstating the fact that it should be kept as a differential diagnosis in every patient presenting with symptoms of chronic rhinosinusitis. Aim of the study was to find out the incidence and clinical manifestations of fungal sinusitis in chronic rhinosinusitis. A prospective study was conducted in JSS Academy of Higher Education and Research, Mysore during a time period of 37 months i.e. November 2015 to December 2018. Total of 190 patients with chronic rhinosinusitis were evaluated with relevant investigations to reach the diagnosis. All patients were subjected to diagnostic nasal endoscopy and CT scan of paranasal sinuses. Patients were then subjected to functional endoscopic sinus surgery and sample collected was sent for KOH stain and fungal culture with histopathology. Fungal rhinosinusitis is on the rise now and it is important to evaluate all cases with caution and keep an eye out for features suggestive of fungal sinusitis as an accurate diagnosis is the key to proper management.

摘要

慢性鼻窦炎是一种全球常见的疾病,其中很大一部分继发于真菌病因,这与普遍认为真菌性鼻窦炎是一种罕见疾病的观点相反,在印度这样的国家更是如此,该国许多邦气候温暖潮湿,糖尿病发病率不断上升,为真菌的生长提供了理想的环境。本研究旨在找出慢性鼻窦炎中真菌性鼻-鼻窦炎的发病率和临床特征,重申在每一位出现慢性鼻窦炎症状的患者中都应将其作为鉴别诊断的事实。该研究的目的是找出慢性鼻窦炎中真菌性鼻窦炎的发病率和临床表现。2015年11月至2018年12月期间,在迈索尔的JSS高等教育与研究学院进行了一项前瞻性研究。共有190例慢性鼻窦炎患者接受了相关检查以明确诊断。所有患者均接受了诊断性鼻内镜检查和鼻窦CT扫描。然后患者接受了功能性鼻内镜鼻窦手术,并将采集的样本送去进行氢氧化钾染色和真菌培养及组织病理学检查。真菌性鼻-鼻窦炎目前呈上升趋势, 谨慎评估所有病例并留意提示真菌性鼻窦炎的特征非常重要,因为准确诊断是妥善管理的关键。

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