Aljohmani L, Abdul-Jalil K, deBlacam C, Murphy G M, O'Sullivan J B
Departments of Plastic and Reconstructive Surgery, Beaumont Hospital, Beaumont road, Dublin 9, Ireland.
JPRAS Open. 2018 Jan 5;15:81-85. doi: 10.1016/j.jpra.2017.11.006. eCollection 2018 Mar.
Pyoderma gangrenosum (PG) is a rare and painful idiopathic skin condition that has one or more areas of chronic ulceration with well demarcated and undermined borders. Bone osteolysis (the pathological destruction of bone tissue) secondary to PG is a rare phenomenon with limited cases reported in children only. This is the first case report of scalp PG with cranial osteolysis in an 80-year-old adult, with an initial presentation mimicking skin carcinoma. This case highlights the importance of a multidisciplinary team (MDT) meeting discussion, diagnosis of PG by exclusion and the successful treatment of this patient's PG eroding to the bone.
坏疽性脓皮病（PG）是一种罕见且疼痛的特发性皮肤病，有一个或多个慢性溃疡区域，边界清晰且呈潜行性。PG继发的骨溶解（骨组织的病理性破坏）是一种罕见现象，仅在儿童中有少数病例报道。这是首例80岁成人头皮PG伴颅骨溶解的病例报告，其最初表现类似皮肤癌。该病例强调了多学科团队（MDT）会议讨论、排除性诊断PG以及成功治疗该患者侵蚀至骨的PG的重要性。
