• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童营养性佝偻病膝冠状面畸形的生长调节:一项前瞻性系列研究及治疗方案

Growth Modulation for Knee Coronal Plane Deformities in Children With Nutritional Rickets: A Prospective Series With Treatment Algorithm.

机构信息

Division of Paediatric Orthopaedics, Department of Orthopaedic Surgery, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2020 Jan 6;4(1). doi: 10.5435/JAAOSGlobal-D-19-00009. eCollection 2020 Jan.

DOI:10.5435/JAAOSGlobal-D-19-00009
PMID:32159063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7028784/
Abstract

UNLABELLED

To report prospectively the radioclinical outcome of guided growth surgery for coronal plane deformities around the knee in young children with nutritional rickets on the intermediate term, to assess the responsiveness of torsional deformities of the tibias to guided growth regarding function and objective clinical parameters, and to propose a treatment algorithm.

METHODS

Fifty children (male:female, 27:23) with knee coronal plane deformities (knees:physes, 86:99), (varum:valgum, 51:35) secondary to nutritional rickets were subjected to femoral and/or tibial temporary hemiepiphysiodesis using a two-hole 8-plate. The mean age at implantation was 3.8 ± 1.5 years (range 2.5 to 5). The mean follow-up was 2.8 years (range 2 to 4). All children received a standing full-length AP radiographs of both lower limbs in neutral rotation to measure the mechanical axis deviation, tibiofemoral angle, and joint orientation angles. Tibial torsion was objectively assessed by measuring the bimalleolar axis.

RESULTS

The radiologic measurements, tibiofemoral angle, mechanical axis deviation, mechanical lateral distal femoral angle, medial proximal tibial angle, and Hilgenreiner-epiphyseal angle, showed a highly statistically significant improvement ( ≤ 0.001). Radiographic outcomes correlated with their clinical counterparts. The mean duration of correction of the mechanical axis was 10.8 ± 2.4 months (7 to 21). The mean follow-up for rebound of the deformity was 1.5 years (range 1 to 3).

CONCLUSION

The radioclinical outcome is rewarding with a tolerable complication profile. The mechanical complications were mostly related to lengthy implant retainment encountered in severe deformities. Internal tibial torsion seems profoundly responsive to correction of coronal plane deformity. And, derotation osteotomies are rarely justified. Our proposed algorithm may be used as a decision-taking guide for achieving the desired growth modulation in a more efficient manner.

摘要

目的

报告儿童营养性佝偻病膝关节冠状面畸形引导生长手术的中期放射临床结果,评估引导生长对胫骨扭转畸形的反应性,以功能和客观临床参数为依据,并提出治疗方案。

方法

50 例(男/女:27/23)膝关节冠状面畸形(膝/骨骺:86/99)(膝内翻/外翻:51/35)的儿童因营养性佝偻病行股骨和/或胫骨临时半骺阻滞术,采用 2 孔 8 板。植入时的平均年龄为 3.8 ± 1.5 岁(范围 2.5 至 5 岁)。平均随访时间为 2.8 年(范围 2 至 4 年)。所有儿童均接受中立位旋转站立位双下肢全长前后位 X 线片,以测量机械轴偏差、胫股角和关节对线角度。胫骨扭转通过测量双踝轴进行客观评估。

结果

影像学测量、胫股角、机械轴偏差、机械外侧股骨远端角、内侧胫骨近端角和 Hilgenreiner 骺板角均有高度统计学意义的改善(≤0.001)。影像学结果与临床结果相关。机械轴矫正的平均持续时间为 10.8 ± 2.4 个月(7 至 21 个月)。畸形复发的平均随访时间为 1.5 年(范围 1 至 3 年)。

结论

放射临床结果令人满意,并发症发生率可接受。机械并发症主要与严重畸形时较长的植入物保留有关。胫骨内旋似乎对冠状面畸形的矫正有明显的反应性。并且,很少需要进行旋转移位截骨术。我们提出的算法可作为决策指南,以更有效的方式实现所需的生长调节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/8b07f3ce2f71/jg9-4-e19.00009-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/37e4be4b61d7/jg9-4-e19.00009-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/4cb8cdc7c0f9/jg9-4-e19.00009-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/47cb68c845d5/jg9-4-e19.00009-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/4663b5c1f90f/jg9-4-e19.00009-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/8b07f3ce2f71/jg9-4-e19.00009-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/37e4be4b61d7/jg9-4-e19.00009-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/4cb8cdc7c0f9/jg9-4-e19.00009-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/47cb68c845d5/jg9-4-e19.00009-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/4663b5c1f90f/jg9-4-e19.00009-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ee2/7028784/8b07f3ce2f71/jg9-4-e19.00009-g005.jpg

相似文献

1
Growth Modulation for Knee Coronal Plane Deformities in Children With Nutritional Rickets: A Prospective Series With Treatment Algorithm.儿童营养性佝偻病膝冠状面畸形的生长调节:一项前瞻性系列研究及治疗方案
J Am Acad Orthop Surg Glob Res Rev. 2020 Jan 6;4(1). doi: 10.5435/JAAOSGlobal-D-19-00009. eCollection 2020 Jan.
2
Hemiepiphysiodesis for Lower Extremity Coronal Plane Angular Correction in the Distal Femur and Proximal Tibia in Children With Achondroplasia.软骨发育不全患儿股骨远端和胫骨近端冠状面角度矫正的半骺板阻滞术。
J Pediatr Orthop. 2023 Sep 1;43(8):e639-e642. doi: 10.1097/BPO.0000000000002442. Epub 2023 May 29.
3
Is surgery always indicated in rachitic coronal knee deformities? Our experience in 198 knees.佝偻病性膝外翻畸形总是需要手术治疗吗?我们对198例患者的经验。
J Orthop Surg (Hong Kong). 2017 Jan;25(1):2309499017693532. doi: 10.1177/2309499017693532.
4
Correcting genu varum and genu valgum in children by guided growth: temporary hemiepiphysiodesis using tension band plates.通过引导生长矫正儿童膝内翻和膝外翻:使用张力带钢板进行临时半骨骺阻滞术
J Bone Joint Surg Br. 2010 Feb;92(2):273-6. doi: 10.1302/0301-620X.92B2.22937.
5
Correction of lower extremity angular deformities in skeletal dysplasia with hemiepiphysiodesis: a preliminary report.半骨骺阻滞术矫正骨骼发育不良中的下肢角畸形:初步报告
J Pediatr Orthop. 2014 Apr-May;34(3):336-45. doi: 10.1097/BPO.0000000000000089.
6
Correction of coronal plane deformities around knee in children with two-hole tension band plates.用两孔张力带钢板矫正儿童膝关节冠状面畸形。
Jt Dis Relat Surg. 2021;32(1):177-184. doi: 10.5606/ehc.2021.78879. Epub 2021 Jan 6.
7
Temporary hemiepiphysiodesis using an eight-plate implant for coronal angular deformity around the knee in children aged less than 10 years: efficacy, complications, occurrence of rebound and risk factors.10 岁以下儿童膝关节冠状面畸形的八板半骺阻滞术:疗效、并发症、反弹发生及危险因素
BMC Musculoskelet Disord. 2021 Jan 9;22(1):53. doi: 10.1186/s12891-020-03915-w.
8
Risk Factors for Rebound After Correction of Genu Valgum in Skeletal Dysplasia Patients Treated by Tension Band Plates.骨骼发育不良患者经张力带钢板治疗后,矫正后复发的风险因素。
J Pediatr Orthop. 2022 Apr 1;42(4):190-194. doi: 10.1097/BPO.0000000000002053.
9
Guided growth for pathological physes: radiographic improvement during realignment.病理性生长板的引导生长:复位过程中的影像学改善
J Pediatr Orthop. 2008 Sep;28(6):632-9. doi: 10.1097/BPO.0b013e3181841fda.
10
Distal Femoral Physeal Bar Resection Combined With Guided Growth for the Treatment of Angular Limb Deformity Associated With Growth Arrest: A Preliminary Report.股骨远端骺板条切除结合骺板阻滞术治疗生长停滞相关性肢体畸形:初步报告。
J Pediatr Orthop. 2020 Nov/Dec;40(10):e958-e962. doi: 10.1097/BPO.0000000000001651.

引用本文的文献

1
[Surgical strategies for osteotomy correction of severe lower limb deformities in hypophosphatemic rickets].[低磷性佝偻病严重下肢畸形截骨矫正的手术策略]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 Jun 15;39(6):701-707. doi: 10.7507/1002-1892.202503128.
2
Surgical outcome of angular deformity correction of lower limbs in rickets: a cross-sectional study.佝偻病下肢成角畸形矫正手术效果的横断面研究。
Eur J Orthop Surg Traumatol. 2024 Jul;34(5):2407-2412. doi: 10.1007/s00590-024-03943-5. Epub 2024 Apr 15.
3
Impact of Intensive Physiotherapy on an Adolescent with Severe Genu Valgum Deformities: A Case Report.

本文引用的文献

1
Guided growth: preliminary results of a multinational study of 967 physes in 537 patients.引导生长:一项针对537例患者967个生长板的多国研究的初步结果。
J Child Orthop. 2018 Feb 1;12(1):91-96. doi: 10.1302/1863-2548.12.170050.
2
Treatment of genu valgum in children by means of temporary hemiepiphysiodesis using eight-plates: short-term findings.使用八孔钢板进行临时半骨骺阻滞术治疗儿童膝外翻:短期结果
BMC Musculoskelet Disord. 2017 Nov 15;18(1):456. doi: 10.1186/s12891-017-1823-7.
3
Guided Growth: Current Perspectives and Future Challenges.
强化物理治疗对一名重度膝外翻畸形青少年的影响:病例报告
Cureus. 2023 Jan 18;15(1):e33907. doi: 10.7759/cureus.33907. eCollection 2023 Jan.
4
Temporary hemiepiphysiodesis using eight-plates for angular deformities of the lower extremities in children with X-linked hypophosphataemic rickets.应用八板暂时骺板阻滞术治疗 X 连锁低磷血症性佝偻病患儿下肢的下肢的角度畸形。
Int Orthop. 2023 Mar;47(3):763-771. doi: 10.1007/s00264-023-05688-y. Epub 2023 Jan 16.
5
Angular Deformities of the Knee in Children Treated with Guided Growth.采用引导性生长治疗的儿童膝关节角畸形
Malays Orthop J. 2021 Jul;15(2):26-35. doi: 10.5704/MOJ.2107.005.
6
X-Linked Hypophosphatemic Rickets: Multisystemic Disorder in Children Requiring Multidisciplinary Management.X 连锁低磷血症性佝偻病:需要多学科管理的儿童多系统疾病。
Front Endocrinol (Lausanne). 2021 Aug 6;12:688309. doi: 10.3389/fendo.2021.688309. eCollection 2021.
7
Correction of coronal plane deformities around knee in children with two-hole tension band plates.用两孔张力带钢板矫正儿童膝关节冠状面畸形。
Jt Dis Relat Surg. 2021;32(1):177-184. doi: 10.5606/ehc.2021.78879. Epub 2021 Jan 6.
引导性生长:当前观点与未来挑战。
JBJS Rev. 2017 Nov;5(11):e1. doi: 10.2106/JBJS.RVW.16.00115.
4
The orthopaedic management of lower limb deformity in hypophosphataemic rickets.低磷性佝偻病下肢畸形的骨科治疗
J Child Orthop. 2017 Aug 1;11(4):298-305. doi: 10.1302/1863-2548.11.170003.
5
Guided growth for angular correction in children: a comparison of two tension band plate designs.儿童角度矫正的引导性生长:两种张力带钢板设计的比较
J Pediatr Orthop B. 2018 Jan;27(1):1-7. doi: 10.1097/BPB.0000000000000492.
6
Correction of lower limb deformities in children with renal osteodystrophy by guided growth technique.采用引导生长技术矫正肾性骨营养不良患儿的下肢畸形。
J Child Orthop. 2017;11(1):79-84. doi: 10.1302/1863-2548-11-160172.
7
Clinical Measurement of the Tibio-femoral Angle in Malay Children.马来儿童胫股角的临床测量
Malays Orthop J. 2015 Jul;9(2):9-12. doi: 10.5704/MOJ.1507.005.
8
Is surgery always indicated in rachitic coronal knee deformities? Our experience in 198 knees.佝偻病性膝外翻畸形总是需要手术治疗吗?我们对198例患者的经验。
J Orthop Surg (Hong Kong). 2017 Jan;25(1):2309499017693532. doi: 10.1177/2309499017693532.
9
Nutritional rickets around the world: an update.全球营养性佝偻病:最新进展
Paediatr Int Child Health. 2017 May;37(2):84-98. doi: 10.1080/20469047.2016.1248170. Epub 2016 Dec 6.
10
Guided growth for tibia vara (Blount's disease).胫骨内翻(布朗特病)的引导性生长
Medicine (Baltimore). 2016 Oct;95(41):e4951. doi: 10.1097/MD.0000000000004951.