Atkin Leanne, Barrett Simon, Chadwick Paul, Callaghan Rosie, Rippon Mark G, Rogers Alan A, Simm Sue
1 Pinderfields.
2 Humber NHS Foundation Trust, The Grange Hessle, 11 Hull Road, Hessle, HU13 9LZ.
J Wound Care. 2020 Mar 2;29(3):174-182. doi: 10.12968/jowc.2020.29.3.174.
The primary objective of this study was to evaluate the fluid management capabilities of a superabsorbent wound dressing (Zetuvit Plus Silicone), with secondary objectives related to parameters that support whether the dressing enables undisturbed healing.
This study was an open labelled non-comparative study. Patients included in the study were selected by the clinical investigator(s) according to whether the patient required a dressing for the management of moderately to highly exuding wounds.
A total of 50 patients were included in the study. Results related to the primary objective demonstrated that the superabsorbent wound dressing was able to absorb all levels of exudate across the range (low to high). At each assessment time point these results show that in 98% of assessments the superabsorbent dressing was rated as 'very good' (91%) or 'good' (7%) at exudate management. Secondary objectives relating to wound bed preparation, healing and management of pain were also positive. Additionally, at the end of each patient treatment, the dressing's fluid management capabilities were rated overall as 'excellent' (100% of cases). There was little pain associated with the wound or at dressing change throughout the study and its flexibility/conformability allowed for comfort and patient satisfaction aligned with increased quality of life. Additionally, inclusion of a silicone adhesive layer allowed painless and atraumatic removal of the dressing, increasing patient comfort, both during wear and at dressing removal, and supported the description of enabling undisturbed wound healing.
The superabsorbent wound dressing achieved the primary objective relating to wound exudate management in all the assessments undertaken in this study. In addition, the silicone interface allowed for undisturbed healing as evidenced by little or no adherence of the dressing to underlying tissue, preventing damage to periwound skin. Overall, the superabsorbent wound dressing with the addition of the silicone interface could offer advantages over other superabsorbent polymer dressings (that might adhere to the wound surface) or silicone wound dressings (that might not have the absorbent properties of this type of dressing).
本研究的主要目的是评估一种高吸水性伤口敷料（Zetuvit Plus Silicone）的液体管理能力，次要目的涉及支持该敷料是否能实现无干扰愈合的相关参数。
本研究为开放标签的非对照研究。研究中的患者由临床研究者根据患者是否需要使用敷料来处理中度至高度渗出性伤口进行选择。
共有50名患者纳入本研究。与主要目的相关的结果表明，高吸水性伤口敷料能够吸收所有水平的渗出液（从低到高）。在每个评估时间点，这些结果显示，在98%的评估中，高吸水性敷料在渗出液管理方面被评为“非常好”（91%）或“好”（7%）。与伤口床准备、愈合和疼痛管理相关的次要目的结果也呈阳性。此外，在每位患者治疗结束时，敷料的液体管理能力总体被评为“优秀”（所有病例的100%）。在整个研究过程中，伤口或换药时几乎没有疼痛，其柔韧性/贴合性带来了舒适感，患者满意度高，生活质量也有所提高。此外，硅酮粘合剂层的加入使敷料能够无痛、无创伤地去除，在佩戴和去除敷料时都增加了患者的舒适度，并支持了实现无干扰伤口愈合的描述。
在本研究进行的所有评估中，高吸水性伤口敷料实现了与伤口渗出液管理相关的主要目标。此外，硅酮界面实现了无干扰愈合，表现为敷料与下层组织几乎没有或没有粘连，防止了对伤口周围皮肤的损伤。总体而言，添加了硅酮界面的高吸水性伤口敷料可能比其他高吸水性聚合物敷料（可能会粘附在伤口表面）或硅酮伤口敷料（可能不具备这种敷料的吸收特性）更具优势。
