Istrian Health Center, Umag Section, Edoardo Pascali 3A, Umag, Croatia,
Psychiatr Danub. 2019 Dec;31(Suppl 5):769-773.
Neurosurgical treatment is one of important way to cure drug resistant epilepsy. After invasive EEG monitoring and the invasive neurosurgical treatment (resective surgery) there are possible complications (intracranial haemorrhage, cortical lesions and infections), however there are possible neuropsyhologic outcomes such as memory outcomes, language outcomes and psychiatric outcomes. The quality of life in epilepsy (QOLIE-31) scale is a self-completed questionnaire which contains seven subscales which address the following aspects: emotional well-being, social functioning, energy/fatigue, cognitive functioning, seizure worry, medication effects and overall quality of life. Our study aimed to examine the quality of life in patients with drug resistant epilepsy who had undergone invasive EEG monitoring and resective neurosurgical treatment through the application of the QOLIE-31 scale.
The study included 9 patients with drug resistant epilepsy who had undergone invasive EEG monitoring followed by resective neurosurgical treatment in the period from 2010 to 2016, and the control group of 15 patients with drug resistant epilepsy who had not undergone neurosurgical procedures. Clinical variables of interest for this study were obtained through phone contact, and the QOLIE-31 scale was applied.
In the domaine of seizure worry, patients in the examined group were more concerned about the seizures (54.7) compared to the examined group (80), as well as in the overal quality of life (examined group 57.5; control group 77.5). Patients in the control group complained more in the domain of antiepileptic therapy (score 70.7) than patients in the examined group (score 100). In the other domains: emotional well-being, energy/fatigue, cognitive functioning, and social functioning there were minor deviations between the examined and control groups.
There was no statistically significant difference between individual QOLIE-31 questionnaires, as well as between the two groups of respondents.
神经外科治疗是治疗耐药性癫痫的重要方法之一。在进行有创脑电图监测和有创神经外科治疗（切除术）后，可能会出现并发症（颅内出血、皮质损伤和感染），但也可能会出现神经心理结局，如记忆结局、语言结局和精神结局。癫痫生活质量问卷（QOLIE-31）是一种自我完成的问卷，包含七个子量表，涵盖以下方面：情绪健康、社交功能、能量/疲劳、认知功能、癫痫发作担忧、药物作用和总体生活质量。我们的研究旨在通过应用 QOLIE-31 量表，检查接受有创脑电图监测和切除性神经外科治疗的耐药性癫痫患者的生活质量。
该研究纳入了 9 例 2010 年至 2016 年期间接受有创脑电图监测和切除性神经外科治疗的耐药性癫痫患者，并纳入了 15 例未接受神经外科手术的耐药性癫痫患者作为对照组。通过电话联系获得了本研究感兴趣的临床变量，并应用 QOLIE-31 量表。
在癫痫发作担忧方面，检查组患者对癫痫发作的担忧程度（54.7）高于对照组（80），总体生活质量也高于对照组（检查组 57.5；对照组 77.5）。对照组患者在抗癫痫治疗方面的抱怨（评分 70.7）多于检查组（评分 100）。在其他领域：情绪健康、能量/疲劳、认知功能和社会功能，检查组和对照组之间存在轻微差异。
个别 QOLIE-31 问卷之间以及两组应答者之间没有统计学上的显著差异。
