Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA.
Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Epilepsy Behav. 2020 Apr;105:106991. doi: 10.1016/j.yebeh.2020.106991. Epub 2020 Mar 8.
We investigated the rate of driving in patients with psychogenic nonepileptic seizures (PNES) from a large cohort in Iran. We hypothesized that these patients commonly do not drive. We also investigated the potential factors that may be associated with driving in these patients.
In this retrospective study, all patients with PNES, who were diagnosed at Shiraz Comprehensive Epilepsy Center, Iran, from 2008 until 2019, were investigated. Age, gender, age at seizure onset, seizure semiology and characteristics, driving history reported by the patients, and video-electroencephalography recordings of all patients were registered routinely.
During the study period, 221 patients with PNES only had the inclusion criteria and were studied. Forty-eight patients (21.7%) reported that they were driving a car in their routine daily lives. Male sex (odds ratio: 13.2; 95% confidence interval: 4.98-35.45; p = 0.0001) and being employed (odds ratio: 8.08; 95% confidence interval: 3.16-20.69; p = 0.0001) were independently significantly associated with driving.
We observed that only about one-fifth of adult patients with PNES reported driving. It is important for the scientific community to develop practice guidelines on how to counsel patients and also the related authorities (e.g., department of motor vehicle authorities) on driving restrictions in people who are affected with PNES.
我们调查了来自伊朗一个大队列的精神性非癫痫性发作（PNES）患者的驾驶率。我们假设这些患者通常不驾车。我们还研究了可能与这些患者驾驶相关的潜在因素。
在这项回顾性研究中，对 2008 年至 2019 年在伊朗 Shiraz 综合癫痫中心诊断为 PNES 的所有患者进行了调查。常规记录了患者的年龄、性别、发病年龄、发作的临床表现和特征、患者自述的驾驶史以及所有患者的视频-脑电图记录。
在研究期间，仅 221 名符合 PNES 纳入标准的患者被纳入研究。48 名患者（21.7%）报告他们在日常生活中开车。男性（优势比：13.2；95%置信区间：4.98-35.45；p=0.0001）和就业（优势比：8.08；95%置信区间：3.16-20.69；p=0.0001）是与驾驶独立显著相关的因素。
我们观察到，只有大约五分之一的成年 PNES 患者报告开车。对于科学界来说，制定如何为患者提供咨询的实践指南以及为受 PNES 影响的患者制定驾驶限制的相关当局（例如机动车管理部门）制定指南非常重要。
