Newman L M, Hendrickx A G
Daniel Baugh Institute, Thomas Jefferson University, Philadelphia.
California Primate Research Center, University of California-Davis.
Am J Primatol. 1984;6(4):337-355. doi: 10.1002/ajp.1350060404.
Fetal development was examined at days 60, 75, 90, 105, 120, or 135 of gestation in 19 thick-tailed bushbaby fetuses (Galago crassicaudatus panganiensis) from 17 normal, timed pregnancies. With the exception of day 135, all fetuses were collected by hysterotomy (gestation = 133 ± 2 days). Various weights and measurements were taken. Although fetal sizes varied widely, crown-rump, crown-heel, upper and lower arm and leg lengths, hand and foot lenghts, and fetal organ weights correlated well with fetal age. Key changes in gross brain morphology and skeletal ossification of cranium, pelvis, tarsals, carpals, and epiphyses were noted. Sternabrae ossification proved highly variable, while ossification in the otic capsule and associated ear structures correlated well with age. These data provide a normal base for studies using fetal developmental parameters whether the purpose is to determine gestational age or to design future studies.
在17例正常、定时妊娠的19只粗尾婴猴胎儿(Galago crassicaudatus panganiensis)的妊娠60、75、90、105、120或135天时,对胎儿发育情况进行了检查。除妊娠135天的胎儿外,所有胎儿均通过子宫切开术收集(妊娠期 = 133 ± 2天)。测量了各种体重和尺寸。尽管胎儿大小差异很大,但顶臀长、顶跟长、上臂和腿长度、手和足长度以及胎儿器官重量与胎龄密切相关。记录了大脑大体形态以及颅骨、骨盆、跗骨、腕骨和骨骺的骨骼骨化的关键变化。胸骨骨化情况差异很大,而听囊及相关耳部结构的骨化与年龄密切相关。这些数据为使用胎儿发育参数的研究提供了正常基线,无论其目的是确定胎龄还是设计未来的研究。