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使用釉基质衍生物(Emd)治疗根尖手术中的联合根尖边缘病变:一项回顾性分析。

The use of Enamel Matrix Derivative (Emd) for Treatment of Combined Apicomarginal Lesions in Apical Surgery: A Retrospective Analysis.

作者信息

Von Arx Thomas, Bosshardt Dieter

机构信息

Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Bern, Switzerland.

Robert K. Schenk Laboratory of Oral Histology, School of Dental Medicine, University of Bern, Bern, Switzerland.

出版信息

Eur Endod J. 2018 Oct 9;3(3):146-152. doi: 10.14744/eej.2018.97269. eCollection 2018.

Abstract

OBJECTIVE

The outcome of apical surgery using modern techniques is favourable. However, the presence of a combined apicomarginal defect may negatively affect the postsurgical healing. The objective of this retrospective analysis was to assess the healing of teeth with apicomarginal defects treated with apical surgery and enamel matrix derivative (EMD).

METHODS

This retrospective study evaluated the application of EMD in apical surgery of 17 teeth with apicomarginal defects. Cases were followed for at least 1 year, and healing was classified based on established clinical and radiographic criteria.

RESULTS

The patient sample included nine females and eight males with a mean age of 50±18.2 years. Maxillary incisors (six lateral and four central) were the most frequently treated teeth. The majority of apicomarginal defects was located on the facial aspect of the root (70.6%) and belonged to defect class I (76.5%). Follow-up periods ranged from 1 to 5 years. Healing was successful in 14 teeth (82.4%).

CONCLUSION

The application of EMD resulted in a similar outcome as in previously published clinical studies related to regenerative techniques for the treatment of apicomarginal defects in conjunction with apical surgery.

摘要

目的

采用现代技术进行根尖手术的效果良好。然而,合并存在根尖边缘缺损可能会对术后愈合产生负面影响。本回顾性分析的目的是评估采用根尖手术和釉基质衍生物(EMD)治疗的根尖边缘缺损牙齿的愈合情况。

方法

本回顾性研究评估了EMD在17颗有根尖边缘缺损牙齿的根尖手术中的应用。对病例进行了至少1年的随访,并根据既定的临床和影像学标准对愈合情况进行分类。

结果

患者样本包括9名女性和8名男性,平均年龄为50±18.2岁。上颌切牙(6颗侧切牙和4颗中切牙)是最常接受治疗的牙齿。大多数根尖边缘缺损位于牙根的唇面(70.6%),属于I类缺损(76.5%)。随访期为1至5年。14颗牙齿(82.4%)愈合成功。

结论

与先前发表的关于联合根尖手术治疗根尖边缘缺损的再生技术的临床研究相比,EMD的应用产生了相似的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79ab/7006581/2289c25df5e6/EEJ-3-146-g001.jpg

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