Dal Prá Ketelin Juliane, de Assis Tristão Stefanny da Silva Santucci, Franco Juliana Bertoldi, Matias Diogo Toledo, Carrillo Camila Merida, de Melo Peres Maria Paula Siqueira, Ribas Priscila Fernandes
Division of Dentistry, Hospital das Clinicas, Medical School, University of São Paulo, São Paulo, Brazil.
Spec Care Dentist. 2020 May;40(3):280-284. doi: 10.1111/scd.12454. Epub 2020 Mar 12.
Pemphigus vulgaris (PV) is a rare and potentially lethal autoimmune disease that affects the skin and mucous membranes. Injuries caused by the disease cause pain, risk of infection, and other complications that result in a high mortality rate. Frequently, management of the PV requires intensive care and a multidisciplinary approach. Oral lesions of PV are usually the first clinical signs of the disease and the last lesions to heal, requiring treatment by a specialized dental team. The aim of this study was to report two clinical cases of PV with involvement of the oral mucosa. The patients were admitted to an intensive care unit, and underwent multidisciplinary management of their condition along with low-level laser therapy. Both cases demonstrated the importance of specialized dental care in improving the quality of life of patients with PV.
寻常型天疱疮(PV)是一种罕见且可能致命的自身免疫性疾病,会影响皮肤和黏膜。该疾病造成的损伤会引起疼痛、感染风险及其他并发症,导致死亡率很高。通常,PV的治疗需要重症监护和多学科方法。PV的口腔病变通常是该疾病的首个临床症状,也是最后愈合的病变,需要由专业牙科团队进行治疗。本研究的目的是报告两例累及口腔黏膜的PV临床病例。患者被收入重症监护病房,并接受了病情的多学科管理以及低强度激光治疗。两例病例均证明了专业牙科护理在改善PV患者生活质量方面的重要性。