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高浓度米诺地尔与二氧化碳联合治疗顽固性雄激素性脱发的疗效:9例报告

Effective combination therapy with high concentration of Minoxidil and Carboxygas in resistant Androgenetic alopecia: Report of nine cases.

作者信息

Nilforooshzadeh Mohammad Ali, Lotfi Elaheh, Heidari-Kharaji Maryam, Zolghadr Sara, Mansouri Parvin

机构信息

Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran.

Jordan Dermatology and Hair Transplantation Center, Tehran.

出版信息

J Cosmet Dermatol. 2020 Nov;19(11):2953-2957. doi: 10.1111/jocd.13362. Epub 2020 Mar 12.

Abstract

BACKGROUND

Androgenetic alopecia (AGA) is widely characterized as the main reason of hair loss which most of the time it has been reported in adults regarding dermatological consultation. Also, it is broadly believed that the progressive miniaturization of hair follicles could be usually different at the age of onset.

AIMS

Over the last decade, detecting and understanding newer genetic basis in AGA lead to provide better therapeutic approaches. We have highlighted on an evidence-based method to treat AGA whose incidence is increasing significantly in our country.

PATIENTS/METHODS: In this study, 9 adults with AGA including 5 women and 4 men, age range of 25-55 years, were treated with a combination of minoxidil (20%) by micro-needling and carboxytherapy mediated by needling. All cases had a normal physical development. Hair numbers (density) and diameter were calculated using trichograms before and after treatment. Hair growth was assessed by the pull test as well.

RESULTS

Our results showed that combination of high concentration of minoxidil and carboxygas extremely can increase the level of hair growth.

CONCLUSION

Our treatment effects on the terminal follicles using needling make sticky follicles become progressively smaller as a result of mechanical forces.

摘要

背景

雄激素性脱发(AGA)被广泛认为是脱发的主要原因,在皮肤科咨询中,大多数情况下报告的是成人AGA。此外,人们普遍认为毛囊的渐进性小型化在发病年龄通常有所不同。

目的

在过去十年中,对AGA新遗传基础的检测和理解为提供更好的治疗方法带来了希望。我们重点介绍了一种基于证据的治疗AGA的方法,在我国,AGA的发病率正在显著上升。

患者/方法:在本研究中,9名AGA成人患者(包括5名女性和4名男性,年龄范围为25 - 55岁)接受了微针注射20%米诺地尔和针刺介导的羧基疗法的联合治疗。所有病例身体发育正常。治疗前后使用毛发图谱计算毛发数量(密度)和直径。还通过拔毛试验评估毛发生长情况。

结果

我们的结果表明,高浓度米诺地尔和羧基气体的联合使用极显著地提高了毛发生长水平。

结论

我们使用针刺对终末毛囊的治疗效果是,由于机械力作用,使粘连的毛囊逐渐变小。

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