Huang Q M, Jiang H R, Wang L S, Zhang B, Wang H J, Wang Z H
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 10;41(2):190-194. doi: 10.3760/cma.j.issn.0254-6450.2020.02.010.
To analyze the prevalence, co-prevalence of cardiovascular metabolic (CM) risk factors in women aged 15-49 years in China, and describe the influence of social economic factors on them. The project data of Nutritional Status and Health Transition of Chinese Residents in 2015 were used. The changes in epidemiological characteristics of central obesity, elevated blood pressure, FPG and TG, decreased HDL-C and co-prevalence of the risk factors in women aged 15-49 years were analyzed. According to the definition of the metabolic syndrome released by the International Diabetes Federation in 2005, five cardio-metabolic risk factors appeared as central obesity, increased triglycerides, decreased HDL-C, increased blood pressure and increased plasma glucose. Co-prevalence of risk factors was defined as detecting 2 or more risk factors in a person at the same time. Multivariate logistic regression model was used to analyze the relationship between socioeconomic factors and metabolic risk factors. In 2015, in women aged 15-49 years in 15 provinces, the detection number (rates) of central obesity, elevated blood pressure, FPG and TG, decreased HDL-C, at least one CM risk factor and co-detection rate of CM risk factors were 944 (47.4), 464 (23.3), 123 (6.2), 327 (16.4), 1 025 (51.5), 1 501 (75.4), and 874 (43.9), respectively. Compared with women aged 15-19 years, the women in age group of 25-, 30-, 35-, 40-, and 45-49 years were more likely to have central obesity (<0.05), the women in age group of 30- 35-, 40-, and 45-49 years were more likely to have elevated blood pressure (<0.05), the women aged 45-49 years were more likely to be affected by one or more CM risk factors (<0.05), but the women in age group 25-29 years group had lower risk for elevated FPG (<0.05). The odds of having central obesity, elevated blood pressure, FPG and TG, decreased HDL-C, at least one CM risk factor and co-prevalence of CM risk factors in women with BMI≥24.0 kg/m(2) were 14.16, 3.05, 2.46, 2.49, 2.42, 9.79 and 7.39 times higher than those in the women with BMI of 18.5-24.0 kg/m(2), respectively. The odds of having elevated FPG and TG in women aged 15-49 years in western China and the odds of having elevated blood pressure and FPG in women aged 15-49 years in eastern China were significantly higher than those in central China. No significant correlations were found between the prevalence and co-prevalence of CM risk factors and income level or urban and rural area residences in women aged 15-49 years. Age, BMI level and living area were the major influencing CM risk factors. The precise prevention and control measures should be taken in time for the adverse changes in CM risk factor prevalence.
分析中国15 - 49岁女性心血管代谢(CM)危险因素的患病率、共患病率,并描述社会经济因素对其的影响。使用2015年中国居民营养与健康状况变迁项目数据,分析15 - 49岁女性中心性肥胖、血压升高、空腹血糖(FPG)和甘油三酯(TG)升高、高密度脂蛋白胆固醇(HDL - C)降低的流行病学特征变化以及危险因素的共患病率。根据国际糖尿病联盟2005年发布的代谢综合征定义,5种心血管代谢危险因素为中心性肥胖、甘油三酯升高、HDL - C降低、血压升高和血糖升高。危险因素共患病率定义为在同一人身上同时检测到2种或更多危险因素。采用多变量逻辑回归模型分析社会经济因素与代谢危险因素之间的关系。2015年,在15个省15 - 49岁女性中,中心性肥胖、血压升高、FPG和TG升高、HDL - C降低、至少一种CM危险因素以及CM危险因素共检率的检测人数(率)分别为944(47.4)、464(23.3)、123(6.2)、327(16.4)、1025(51.5)、1501(75.4)和874(43.9)。与15 - 19岁女性相比,25 -、30 -、35 -、40 -以及45 - 49岁年龄组的女性更易发生中心性肥胖(<0.05),30 - 35 -、40 -以及45 - 49岁年龄组的女性更易出现血压升高(<0.05),45 - 49岁的女性更易受一种或多种CM危险因素影响(<0.05),但25 - 29岁年龄组的女性FPG升高风险较低(<0.05)。体重指数(BMI)≥24.0 kg/m²的女性发生中心性肥胖、血压升高、FPG和TG升高、HDL - C降低、至少一种CM危险因素以及CM危险因素共患病率的比值分别比BMI为18.5 - 24.0 kg/m²的女性高14.16、3.05、2.46、2.49、2.42、9.79和7.39倍。中国西部15 - 49岁女性FPG和TG升高的比值以及中国东部15 - 49岁女性血压升高和FPG升高的比值显著高于中部地区。15 - 49岁女性CM危险因素的患病率和共患病率与收入水平或城乡居住地之间未发现显著相关性。年龄、BMI水平和居住地区是影响CM危险因素的主要因素。应及时针对CM危险因素患病率的不利变化采取精准防控措施。