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成人注意缺陷多动障碍的情绪调节障碍:一项荟萃分析。

Emotion dysregulation in adults with attention deficit hyperactivity disorder: a meta-analysis.

机构信息

Department of Psychology, Child and Adolescent Clinical Psychology Group, Marburg University, Gutenbergstr.18, 35037, Marburg, Germany.

出版信息

BMC Psychiatry. 2020 Mar 12;20(1):120. doi: 10.1186/s12888-020-2442-7.

Abstract

BACKGROUND

Emotional symptoms are increasingly considered a core feature of attention deficit/hyperactivity disorder (ADHD). We aimed to quantify the evidence of emotional dysregulation and its respective facets in individuals with adult ADHD compared to healthy controls using meta-analysis.

METHODS

Two electronic databases (PubMed, PsycINFO) were reviewed to identify studies. Studies were eligible for inclusion that had reports on any measure of emotion (dys) regulation in adults (> 18 years of age) in clinically diagnosed patients with ADHD as well as healthy control participants. We included a total of 13 studies (N = 2535) to assess (1) the standardized mean difference in emotion dysregulation (ED) as a general factor and its specific facets (i.e., emotional lability, negative emotional responses, and emotion recognition) between adults with ADHD and healthy controls; and (2) the association between ADHD symptom severity and ED.

RESULTS

Compared to healthy controls, adults with ADHD revealed significantly higher levels of general ED (Hedges' g = 1.17, p < 0.001; Hedges' g is the adjusted effect size). With regard to intermediate dimensions of ED, emotional lability exhibited the strongest weighted effect (Hedges' g = 1.20, CI [0.57, 1.83], p < 0.001). Furthermore, symptom severity and general ED correlated significantly (r = 0.54, p < 0.001). Regarding intermediate dimensions of ED, negative emotional responses correlated closely with ADHD symptom severity (r = 0.63, p < 0.001) and emotional lability (r = 0.52, p < 0.001).

CONCLUSIONS

Our findings support ED symptoms as a core feature of ADHD's psychopathology. With respect to dimensions of ED, emotional lability, and negative emotional responses play a more definitive role in the psychopathology of adults with ADHD. Due to insufficient statistical reports in the included studies, we could not perform meta-regressions to control the role of moderator variables.

摘要

背景

情绪症状越来越被认为是注意力缺陷/多动障碍(ADHD)的核心特征。我们旨在使用荟萃分析量化成年 ADHD 患者与健康对照组相比情绪失调及其各个方面的证据。

方法

综述了两个电子数据库(PubMed、PsycINFO)以确定研究。符合纳入标准的研究报告了在临床诊断为 ADHD 的成年患者(> 18 岁)和健康对照参与者中使用任何情绪(失调)调节措施的研究。我们共纳入了 13 项研究(N = 2535),以评估(1)ADHD 成人中情绪失调(ED)的标准化均数差作为一般因素及其特定方面(即情绪不稳定性、负性情绪反应和情绪识别)与健康对照组之间的差异;(2)ADHD 症状严重程度与 ED 的相关性。

结果

与健康对照组相比,ADHD 成人的一般 ED 水平显著更高(Hedges' g = 1.17,p < 0.001;Hedges' g 是调整后的效应量)。关于 ED 的中间维度,情绪不稳定性的加权效应最强(Hedges' g = 1.20,CI [0.57,1.83],p < 0.001)。此外,症状严重程度与一般 ED 显著相关(r = 0.54,p < 0.001)。关于 ED 的中间维度,负性情绪反应与 ADHD 症状严重程度密切相关(r = 0.63,p < 0.001)和情绪不稳定性(r = 0.52,p < 0.001)。

结论

我们的研究结果支持 ED 症状是 ADHD 病理生理学的核心特征。就 ED 的维度而言,情绪不稳定性和负性情绪反应在 ADHD 成人的病理生理学中起更决定性的作用。由于纳入研究中统计报告不足,我们无法进行元回归以控制调节变量的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6b5/7069054/47da418fac06/12888_2020_2442_Fig1_HTML.jpg

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