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基于CT的评分系统在评估胰腺炎严重程度中的应用。

Use of CT-Based Scoring System in Assessment of Pancreatitis Severity.

作者信息

Ermekova Madina

机构信息

Karaganda State Medical University, Gogol Street 40, Karagandy 100000, Kazakhstan.

出版信息

Open Access Maced J Med Sci. 2019 Nov 14;7(23):3997-4003. doi: 10.3889/oamjms.2019.597. eCollection 2019 Dec 15.

Abstract

BACKGROUND

Severity of AP is an important indicator of death rate, playing a crucial role in defining a correct dealing with a patient at his/her initial admission, in deciding on the need to transfer a patient to the intensive care unit. Many studies point out a direct relation between the death rate and the number of affected organs. In light of this, looking for the new criteria of multiple organ failure is still useful in clinical practice. Typically, assessment of multiple organ failure with patients undergoing treatment in the intensive care unit is carried out with the use of various integrated scores based both on clinical laboratory assessment of patient's condition and on data obtained by advanced imaging methods. However, many scientists point out that the facilities of diagnostic radiology, including in particularly computerised tomography, are not used to the full extent.

AIM

We developed a CT score for assessment of pancreatitis severity that takes into consideration not only alterations of the pancreas but also enables evaluation of multiple organ failure with the examined patients.

METHODS

We have examined 100 patients with suspected pancreatitis. Among them 30 patients had pancreatitis without alterations of the vital organs; 70 patients had alterations of the vital organs, suffered organ or multiple organ failure and received treatment in the surgery unit and intensive care unit of the Department of Surgical Conditions of Karaganda Medical University.

RESULTS

Because of CT results, based on the proposed score, we assessed a degree of pancreas necrosis, analysed the relation between organ failure and degree of pancreas necrosis. Finally, we evaluated the connection between multiple organ failure and the specific failure of one organ and the presence of necrosis and death rate.

CONCLUSION

The proposed score for CT-based assessment of pancreatitis severity can be used not only for identification but also for prediction of organ failure at the early stage of pancreatitis to a high accuracy as compared to conventional CT systems for assessment of the condition of patients affected by pancreatitis. It can also be used to differentiate the severity of organ failure and the number of affected organs.

摘要

背景

急性胰腺炎(AP)的严重程度是死亡率的重要指标,在患者初次入院时确定正确的治疗方案以及决定是否需要将患者转入重症监护病房方面起着关键作用。许多研究指出死亡率与受影响器官的数量之间存在直接关系。有鉴于此,寻找多器官功能衰竭的新标准在临床实践中仍然很有用。通常,对在重症监护病房接受治疗的患者进行多器官功能衰竭评估时,会使用各种综合评分,这些评分既基于对患者病情的临床实验室评估,也基于通过先进成像方法获得的数据。然而,许多科学家指出,包括计算机断层扫描在内的诊断放射学设施并未得到充分利用。

目的

我们开发了一种用于评估胰腺炎严重程度的CT评分,该评分不仅考虑胰腺的改变,还能对受检患者的多器官功能衰竭进行评估。

方法

我们检查了100例疑似胰腺炎患者。其中30例患者患有胰腺炎但重要器官无改变;70例患者重要器官有改变,出现器官或多器官功能衰竭,并在卡拉干达医科大学外科疾病系的外科病房和重症监护病房接受治疗。

结果

基于所提出的评分,根据CT结果,我们评估了胰腺坏死程度,分析了器官功能衰竭与胰腺坏死程度之间的关系。最后,我们评估了多器官功能衰竭与单个器官的特定衰竭以及坏死和死亡率之间的联系。

结论

与传统的用于评估胰腺炎患者病情的CT系统相比,所提出的基于CT的胰腺炎严重程度评估评分不仅可用于识别,还能高精度地预测胰腺炎早期的器官功能衰竭。它还可用于区分器官功能衰竭的严重程度和受影响器官的数量。

相似文献

1
Use of CT-Based Scoring System in Assessment of Pancreatitis Severity.基于CT的评分系统在评估胰腺炎严重程度中的应用。
Open Access Maced J Med Sci. 2019 Nov 14;7(23):3997-4003. doi: 10.3889/oamjms.2019.597. eCollection 2019 Dec 15.

本文引用的文献

10
Pancreatitis-imaging approach.胰腺炎的影像学检查方法
World J Gastrointest Pathophysiol. 2014 Aug 15;5(3):252-70. doi: 10.4291/wjgp.v5.i3.252.

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