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针对有酒精使用问题的危重症幸存者的康复导航计划的试点随机试验。

Pilot Randomized Trial of a Recovery Navigator Program for Survivors of Critical Illness With Problematic Alcohol Use.

作者信息

Clark Brendan J, Sorrell Tanya, Hodapp Rachel M, Reed Kathryne, Moss Marc, Aagaard Laurra, Cook Paul F

机构信息

Department of Medicine, University of Colorado School of Medicine, Aurora, CO.

Biobehavioral Symptom Science Group, University of Colorado College of Nursing, Aurora, CO.

出版信息

Crit Care Explor. 2019 Oct 14;1(10):e0051. doi: 10.1097/CCE.0000000000000051. eCollection 2019 Oct.

Abstract

UNLABELLED

Many survivors of critical illness have problematic alcohol use, associated with risk of death and hospital readmission. We tested the feasibility, acceptability, treatment fidelity, and potential efficacy of a customized alcohol intervention for patients in ICUs. The intervention was delivered by a Recovery Navigator using principles of motivational interviewing and shared decision-making.

DESIGN

Pilot randomized trial.

SETTING

Two urban ICUs in Denver, CO.

PATIENTS

Patients with problematic alcohol use were enrolled prior to hospital discharge.

INTERVENTIONS

Patients were randomly assigned to usual care, single-session motivational interviewing and shared decision-making, or multisession motivational interviewing and shared decision-making.

MEASUREMENTS AND MAIN RESULTS

We assessed feasibility via enrollment and attrition, acceptability via patient satisfaction (Client Satisfaction Questionnaire-8), fidelity via observation and questionnaires, and potential efficacy via group means and CIs on measures of alcohol use, psychiatric symptoms, cognition, and other alcohol-related problems. Over 18 months, we offered the study to 111 patients, enrolled 47, and randomized 36; refusals were mainly due to stigma or patients' desire to handle problems on their own. Groups were similar at baseline, and 67% of patients met criteria for alcohol use disorder. Average patient satisfaction was high (mean = 28/32) regardless of group assignment. Sessions were delivered with 98% adherence to motivational interviewing principles and excellent motivational interviewing spirit; patients perceived the intervention to be more autonomy supportive than usual care. Group means after 6 months suggested that patients receiving the intervention might improve on measures such as alcohol use, psychiatric symptoms, legal problems, and days of paid work; however, they did not receive more substance use treatment. All results were nonsignificant due to small sample size.

CONCLUSIONS

A Recovery Navigator intervention was feasible and acceptable for delivering high-fidelity brief interventions to ICU patients. Changes in alcohol-related problems with motivational interviewing and shared decision-making were nonsignificant but clinically meaningful in size. A full-scale randomized trial of motivational interviewing and shared decision-making is warranted.

摘要

未标注

许多危重病幸存者存在酒精使用问题,这与死亡风险和再次入院风险相关。我们测试了一种针对重症监护病房(ICU)患者的定制酒精干预措施的可行性、可接受性、治疗依从性和潜在疗效。该干预措施由康复导航员依据动机性访谈和共同决策原则实施。

设计

试点随机试验。

地点

科罗拉多州丹佛市的两家城市ICU。

患者

存在酒精使用问题的患者在出院前入组。

干预措施

患者被随机分配至常规护理组、单节次动机性访谈和共同决策组或多节次动机性访谈和共同决策组。

测量指标及主要结果

我们通过入组和失访评估可行性,通过患者满意度(客户满意度问卷 - 8)评估可接受性,通过观察和问卷评估依从性,通过组均值和置信区间评估酒精使用、精神症状、认知及其他与酒精相关问题的潜在疗效。在18个月期间,我们向111名患者提供了该研究,47名患者入组,36名患者被随机分组;拒绝参与主要是因为耻辱感或患者希望自行解决问题。各小组在基线时相似,67%的患者符合酒精使用障碍标准。无论分组如何,患者平均满意度都很高(均值 = 28/32)。干预节次的实施符合动机性访谈原则的比例为98%,且具有出色的动机性访谈氛围;患者认为该干预比常规护理更支持自主性。6个月后的组均值表明,接受干预的患者在酒精使用、精神症状、法律问题和带薪工作天数等指标上可能有所改善;然而,他们接受的物质使用治疗并未增多。由于样本量小,所有结果均无统计学意义。

结论

康复导航员干预措施对于向ICU患者提供高保真简短干预是可行且可接受的。动机性访谈和共同决策导致的与酒精相关问题的变化虽无统计学意义,但在临床上具有一定意义。有必要开展动机性访谈和共同决策的全面随机试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c5f/7063892/0589a2d47120/cc9-1-e0051-g001.jpg

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