Pervaiz Abdullah M, Akhtar Raheel, Mercado Melissa
Department of Medicine, University of Massachusetts Medical School- Baystate, Springfield, MA.
Department of Medicine, Windsor University School of Medicine, Cayon, St. Kitts and Nevis.
Crit Care Explor. 2019 Sep 4;1(9):e0041. doi: 10.1097/CCE.0000000000000041. eCollection 2019 Sep.
infection is known to cause a variety of neurologic complications, most involving the CNS, however, rarely have cases of affecting the peripheral nervous system been reported in literature. We report a case of toxin-mediated motor polyneuropathy in a patient presenting with acute flaccid quadriplegia.
A 64-year-old female with mantle cell lymphoma on oral chemotherapy with ibrutinib presents with malaise and progressive ascending bilateral lower extremity weakness. Blood cultures resulted positive for methicillin-sensitive , and she was initiated on antibiotics. Imaging studies and laboratory workup were negative for other causes of acute flaccid quadriplegia. Patient had complete resolution of her neurologic deficits with antibiotic therapy. It was determined that the likely diagnosis was Staphylococcus toxin-mediated motor polyneuropathy.
Staphylococcal-mediated motor polyneuropathy resulting in acute flaccid quadriplegia is a rare but treatable complication of bacteremia and should remain a diagnosis of exclusion.
已知感染会引起多种神经并发症，大多数累及中枢神经系统，然而，文献中很少报道影响周围神经系统的病例。我们报告一例毒素介导的运动性多发性神经病患者，该患者表现为急性弛缓性四肢瘫。
一名64岁女性，患有套细胞淋巴瘤，正在接受伊布替尼口服化疗，出现不适和进行性双侧下肢无力。血培养结果显示对甲氧西林敏感的[具体细菌名称未给出]呈阳性，她开始接受抗生素治疗。影像学检查和实验室检查未发现急性弛缓性四肢瘫的其他病因。患者经抗生素治疗后神经功能缺损完全恢复。确定可能的诊断为葡萄球菌毒素介导的运动性多发性神经病。
葡萄球菌介导的运动性多发性神经病导致急性弛缓性四肢瘫是一种罕见但可治疗的菌血症并发症，应始终作为排除性诊断。
