Unit for Clinical Alcohol Research, Unit for Psychiatric Research, Department of Clinical Research, University of Southern Denmark, J.B. Winsløws Vej 18, 5000 Odense C.
Psychiatric Hospital, University section, Region of Southern Denmark, J.B. Winsløws Vej 18, 5000 Odense C.
Alcohol Alcohol. 2020 Apr 16;55(3):291-298. doi: 10.1093/alcalc/agaa018.
To identify predictors of readmission to outpatient treatment for alcohol use disorder (AUD) with a view to identifying underlying mechanisms for preventing relapse.
A consecutive clinical cohort of 2130 AUD outpatients treated between 1 January 2006 and 1 June 2016 was studied. Data were collected by means of the Addiction Severity Index upon treatment entry and at discharge. Outcome measures were readmission to outpatient treatment and time to readmission. Potential predictors were tested for significance using Cox Proportional Hazards multivariate analysis.
A total of 22% were readmitted during the follow-up time. Patients readmitted within 1 year of treatment conclusion differed significantly from those not readmitted on age, cohabitation status and completion status of index treatment. Significant predictors of readmission during follow-up time were younger age (hazard ratio (HR) = 0.99, 95% confidence interval (CI), 0.98-1.00), history of psychiatric illness (HR = 1.24, 95% CI, 1.02-1.50), drop-out from index treatment (HR = 1.41, 95% CI, 1.15-1.72) and length of index treatment (HR = 1.02, 95% CI, 1.00-1.04).
Premature drop-out from treatment, a history of psychiatric illness, younger age and longer treatment episodes appear to be the most important predictors of readmission.
确定导致酒精使用障碍（AUD）门诊治疗再入院的预测因素，以期确定预防复发的潜在机制。
研究了 2006 年 1 月 1 日至 2016 年 6 月 1 日期间接受治疗的连续临床队列 2130 名 AUD 门诊患者。在治疗开始时和出院时，通过成瘾严重程度指数收集数据。主要结果为门诊治疗再入院和再入院时间。使用 Cox 比例风险多变量分析测试潜在预测因子的显著性。
随访期间共有 22%的患者再入院。在治疗结束后 1 年内接受再入院治疗的患者与未接受再入院治疗的患者在年龄、同居状况和指数治疗完成情况方面存在显著差异。随访期间再入院的显著预测因子为年龄较小（风险比（HR）=0.99，95%置信区间（CI），0.98-1.00）、有精神病史（HR=1.24，95%CI，1.02-1.50）、指数治疗辍学（HR=1.41，95%CI，1.15-1.72）和指数治疗时长（HR=1.02，95%CI，1.00-1.04）。
过早退出治疗、有精神病史、年龄较小和治疗时间较长似乎是再入院的最重要预测因素。
