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新西兰克赖斯特彻奇市 2019 年 3 月大规模枪击事件中的输血治疗分析。

Analysis of transfusion therapy during the March 2019 mass shooting incident in Christchurch, New Zealand.

机构信息

New Zealand Blood Service, Christchurch, New Zealand.

Canterbury District Health Board, Christchurch, New Zealand.

出版信息

Vox Sang. 2020 Jul;115(5):424-432. doi: 10.1111/vox.12907. Epub 2020 Mar 12.

Abstract

BACKGROUND AND OBJECTIVE

A mass casualty incident occurred in Christchurch in March 2019. Thirty-seven patients with gunshot wounds were admitted. We describe and analyse the transfusion management of these casualties.

METHODS

Data on demographics, injury and laboratory characteristics, and transfusions are summarized using descriptive statistics. Relationships between variables are examined using Pearson's and Spearman's rank correlations. Univariate analysis of explanatory variables is performed to determine the best early predictors of transfusion requirements. The characteristics of massive transfusion and non-massive transfusion cases are compared using the t- and Mann-Whitney tests.

RESULTS

Sixty-five per cent received transfusions. Initial Hb, platelet counts and clotting results were mostly normal. On average, each gunshot wound patient was transfused 4, 3·1, 1·2 and 0·4 units of RBC, FFP, cryoprecipitate and platelets, respectively, on the day. Base excess was the single best predictor of transfusion requirements.

CONCLUSIONS

A greater proportion of those with gunshot wounds in this incident were transfused than in other such incidents. Transfusion requirements for patients varied but were generally modest. Blood component transfusion ratios were close to that recommended. The role of base excess as a predictor of transfusion requirements in patients with similar injuries needs more study.

摘要

背景与目的

2019 年 3 月,克赖斯特彻奇发生一起大规模人员伤亡事件。有 37 名枪伤患者入院。我们描述并分析了这些伤员的输血管理情况。

方法

使用描述性统计方法对人口统计学、损伤和实验室特征以及输血数据进行总结。使用 Pearson 和 Spearman 秩相关检验分析变量之间的关系。使用单变量分析对解释变量进行分析,以确定输血需求的最佳早期预测指标。使用 t 检验和 Mann-Whitney 检验比较大量输血和非大量输血病例的特征。

结果

65%的患者接受了输血。初始血红蛋白、血小板计数和凝血结果大多正常。平均而言,每位枪伤患者在当天分别输注了 4、3.1、1.2 和 0.4 单位红细胞、FFP、冷沉淀和血小板。碱剩余是输血需求的唯一最佳预测指标。

结论

在这次事件中,有更多的枪伤患者接受了输血,比其他类似事件中的患者更多。患者的输血需求各不相同,但通常较为适中。血液成分的输血比例接近推荐值。碱剩余作为预测类似损伤患者输血需求的指标,需要进一步研究。

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