Department of Surgery, Chonnam National University Medical School, Gwangju 61469, South Korea.
Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, South Korea.
Chem Commun (Camb). 2020 Apr 14;56(30):4180-4183. doi: 10.1039/d0cc01366h.
A tumor-targeted near-infrared (NIR) fluorophore CA800SO3 was developed for fluorescence-guided phototherapy. This new type of NIR fluorophore showed high tumor targetability based on the structure-inherent targeting approach. This fluorophore generated sufficient hyperthermia and reactive oxygen species (ROS) simultaneously for synergistic cancer phototherapy, induced by an 808 nm laser irradiation.
一种肿瘤靶向近红外（NIR）荧光染料 CA800SO3 被开发用于荧光引导光疗。这种新型 NIR 荧光染料基于结构固有靶向方法表现出高肿瘤靶向性。该荧光染料在 808nm 激光照射下，同时产生足够的热疗和活性氧（ROS），从而协同进行癌症光疗。
